1-(2,6-dichloro-pyridine-4-carbonyl)-3-(2,3,4-trifluoro-phenyl)-thiourea

Base Information

Chemical Name:1-(2,6-dichloro-pyridine-4-carbonyl)-3-(2,3,4-trifluoro-phenyl)-thiourea
CAS No.:1145355-31-2
Molecular Formula:C₁₃H₆Cl₂F₃N₃OS
Molecular Weight:380.177
Hs Code.:

Synonyms:1-(2,6-dichloro-pyridine-4-carbonyl)-3-(2,3,4-trifluoro-phenyl)-thiourea

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Chemical Property of 1-(2,6-dichloro-pyridine-4-carbonyl)-3-(2,3,4-trifluoro-phenyl)-thiourea

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Technology Process of 1-(2,6-dichloro-pyridine-4-carbonyl)-3-(2,3,4-trifluoro-phenyl)-thiourea

There total 1 articles about 1-(2,6-dichloro-pyridine-4-carbonyl)-3-(2,3,4-trifluoro-phenyl)-thiourea which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

: 224635-75-0
2,3,4-trifluorobenzenamine hydrochloride

: ammonium thiocyanate

: 42521-08-4
2,6-dichloroisonicotinoyl chloride

: 1145355-31-2
1-(2,6-dichloro-pyridine-4-carbonyl)-3-(2,3,4-trifluoro-phenyl)-thiourea

Guidance literature:: ammonium thiocyanate; 2,6-dichloroisonicotinoyl chloride; In acetone; for 0.5h;

2,3,4-trifluorobenzenamine hydrochloride; In acetone; at 20 ℃; for 2h;

Reference yield: 32.0%

: 1145355-31-2
1-(2,6-dichloro-pyridine-4-carbonyl)-3-(2,3,4-trifluoro-phenyl)-thiourea

: 74-88-4
methyl iodide

: 1145355-34-5
1-(2,6-dichloro-pyridine-4-carbonyl)-2-methyl-3-(2,3,4-trifluoro-phenyl)-isothiourea

Guidance literature:: 1-(2,6-dichloro-pyridine-4-carbonyl)-3-(2,3,4-trifluoro-phenyl)-thiourea; With sodium hydride; In tetrahydrofuran; at 0 ℃; for 0.25h;

methyl iodide; In tetrahydrofuran; at 20 ℃; for 2h;