2-(4-Butoxy-3-fluorophenyl)acetohydroxamic acid

Base Information

• Chemical Name: 2-(4-Butoxy-3-fluorophenyl)acetohydroxamic acid
• CAS No.: 15560-65-3
• Molecular Formula: C₁₂H₁₆FNO₃
• Molecular Weight: 241.262
• Hs Code.: 2924299090
• Mol file: 15560-65-3.mol

Synonyms:Acetohydroxamicacid, 2-(4-butoxy-3-fluorophenyl)- (8CI)

Chemical Property of 2-(4-Butoxy-3-fluorophenyl)acetohydroxamic acid

Chemical Property:

• PSA: 62.05000
• Density: 1.185g/cm³
• LogP: 2.89280

Purity/Quality:

99% ^*data from raw suppliers

2-(4-BUTOXY-3-FLUOROPHENYL)ACETOHYDROXAMIC ACID 95.00% ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 2-(4-Butoxy-3-fluorophenyl)acetohydroxamic acid

There total 3 articles about 2-(4-Butoxy-3-fluorophenyl)acetohydroxamic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-butoxy-2-fluorobenzene (20781-61-7) → N-Hydroxy-3-fluoro-4-butoxyphenylacetamide (15560-65-3)

Guidance literature:

Multi-step reaction with 2 steps

1: (i) HCl, (ii) /BRN= 3587243/, DMSO, (iii) /BRN= 1718733/, H₂SO₄

2: NH₂OH*HCl, NaOMe / methanol / Heating

With hydroxylamine hydrochloride; sodium methylate; In methanol;

Reference yield:

(4-Butoxy-3-fluoro-phenyl)-acetic acid ethyl ester (15560-91-5) → N-Hydroxy-3-fluoro-4-butoxyphenylacetamide (15560-65-3)

Guidance literature:

With hydroxylamine hydrochloride; sodium methylate; In methanol; Heating;

Reference yield:

→ N-Hydroxy-3-fluoro-4-butoxyphenylacetamide (15560-65-3)

Guidance literature:

Ester, HONH2*HCl, Me., Na;

upstream raw materials:

(4-Butoxy-3-fluoro-phenyl)-acetic acid ethyl ester

1-butoxy-2-fluorobenzene

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