Technology Process of C38H33N3O4
There total 11 articles about C38H33N3O4 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
hydroxylamine hydrochloride; triethylamine;
In
dimethyl sulfoxide;
at 70 ℃;
for 4h;
DOI:10.1016/j.bmcl.2013.02.013
- Guidance literature:
-
Multi-step reaction with 5 steps
1.1: tris-(o-tolyl)phosphine; sodium hydrogencarbonate / water; 1,2-dimethoxyethane / 0.25 h / Inert atmosphere
1.2: 2 h / 90 °C / Inert atmosphere
1.3: 1 h / 20 °C
2.1: zinc(II) chloride / toluene / Dean-Stark
3.1: indium(III) triflate / acetonitrile / 5 h / Reflux; Molecular sieve
4.1: Chiralcel OG column / ethanol; hexane / 20 °C / Resolution of racemate
5.1: hydroxylamine hydrochloride; triethylamine / dimethyl sulfoxide / 4 h / 70 °C
With
indium(III) triflate; hydroxylamine hydrochloride; sodium hydrogencarbonate; triethylamine; tris-(o-tolyl)phosphine; zinc(II) chloride;
In
1,2-dimethoxyethane; ethanol; hexane; water; dimethyl sulfoxide; toluene; acetonitrile;
1.1: |Suzuki-Miyaura Coupling / 1.2: |Suzuki-Miyaura Coupling;
DOI:10.1016/j.bmcl.2013.02.013
- Guidance literature:
-
Multi-step reaction with 3 steps
1: indium(III) triflate / acetonitrile / 5 h / Reflux; Molecular sieve
2: Chiralcel OG column / ethanol; hexane / 20 °C / Resolution of racemate
3: hydroxylamine hydrochloride; triethylamine / dimethyl sulfoxide / 4 h / 70 °C
With
indium(III) triflate; hydroxylamine hydrochloride; triethylamine;
In
ethanol; hexane; dimethyl sulfoxide; acetonitrile;
DOI:10.1016/j.bmcl.2013.02.013
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