7-(benzoylamino)-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene

Base Information

• Chemical Name: 7-(benzoylamino)-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene
• CAS No.: 106731-49-1
• Molecular Formula: C₁₇H₁₄N₂O
• Molecular Weight: 262.311
• Mol file: 106731-49-1.mol

Synonyms:7-(benzoylamino)-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene

Chemical Property of 7-(benzoylamino)-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 7-(benzoylamino)-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene

There total 3 articles about 7-(benzoylamino)-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 47.0%

benzoyl chloride (98-88-4) + 7-amino-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene (106731-51-5,113972-73-9,113974-01-9) → 7-(benzoylamino)-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene (106731-49-1)

Guidance literature:

With sodium carbonate; In diethyl ether; at 0 ℃; for 0.25h;

DOI:10.1021/jo00261a011

Reference yield:

7-<<<(9-fluorenylmethyl)oxy>carbonyl>amino>-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene (106731-46-8,113972-75-1,113972-76-2) → 7-(benzoylamino)-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene (106731-49-1)

Guidance literature:

Multi-step reaction with 2 steps

1: Et₂N / acetonitrile; CH₂Cl₂ / 0 °C

With diethylamine; In dichloromethane; acetonitrile;

DOI:10.1039/c39860000747

Reference yield:

1,4-dihydro-1,4-epiazano-naphthalene (5176-20-5) → 7-(benzoylamino)-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene (106731-49-1)

Guidance literature:

Multi-step reaction with 2 steps

1: O-mesitylenesulphonylhydroxylamine / -10 °C

With mesitylenesulfonylhydroxylamine;

DOI:10.1039/c39860000747

upstream raw materials:

benzoyl chloride

7-amino-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene

1,4-dihydro-1,4-epiazano-naphthalene

7-<<<(9-fluorenylmethyl)oxy>carbonyl>amino>-2,3-benzo-7-azabicyclo<2.2.1>hepta-2,5-diene

Downstream raw materials:

naphthalene

1-Benzoyl-2-(1-naphthyl)hydrazine

N'-benzoylbenzohydrazide

7-(benzoylamino)-7-azabicyclo<4.1.0>heptane