2',3'-O-isopropylidene-5'-O-triphenylmethyl-1-<(ethoxycarbonyl)methyl>-inosine

Base Information

Chemical Name:2',3'-O-isopropylidene-5'-O-triphenylmethyl-1-<(ethoxycarbonyl)methyl>-inosine
CAS No.:157762-04-4
Molecular Formula:C₃₆H₃₆N₄O₇
Molecular Weight:636.704
Hs Code.:

Synonyms:2',3'-O-isopropylidene-5'-O-triphenylmethyl-1-<(ethoxycarbonyl)methyl>-inosine

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 2',3'-O-isopropylidene-5'-O-triphenylmethyl-1-<(ethoxycarbonyl)methyl>-inosine

Chemical Property:

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Technology Process of 2',3'-O-isopropylidene-5'-O-triphenylmethyl-1-<(ethoxycarbonyl)methyl>-inosine

There total 1 articles about 2',3'-O-isopropylidene-5'-O-triphenylmethyl-1-<(ethoxycarbonyl)methyl>-inosine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 105-36-2
ethyl bromoacetate

: 9-((3aR,4R,6R,6aR)-2,2-Dimethyl-6-trityloxymethyl-tetrahydro-furo[3,4-d][1,3]dioxol-4-yl)-1,9-dihydro-purin-6-one

: 157762-04-4
2',3'-O-isopropylidene-5'-O-triphenylmethyl-1-<(ethoxycarbonyl)methyl>-inosine

Guidance literature:: With 18-crown-6 ether; potassium carbonate; In tetrahydrofuran; for 4h; Ambient temperature;
DOI:10.1080/15257779408012169

Reference yield:

: 157762-04-4
2',3'-O-isopropylidene-5'-O-triphenylmethyl-1-<(ethoxycarbonyl)methyl>-inosine

: 157762-06-6
5-amino-1-(2,3-O-isopropylidene-5-O-truphenylmethyl-β-D-ribofuranosyl)imidazole-4-(N-carboxymethyl)carboxamide

Guidance literature:: With sodium hydroxide; In ethanol; for 3h; Heating;
DOI:10.1080/15257779408012169

Reference yield:

: 157762-04-4
2',3'-O-isopropylidene-5'-O-triphenylmethyl-1-<(ethoxycarbonyl)methyl>-inosine

: 157762-07-7
5-amino-1-(2,3-O-isopropylidene-5-O-triphenylmethyl-β-D-ribofuranosyl)imidazole-4-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1: aq. NaOH / ethanol / 3 h / Heating

2: 70 percent / methanol

With sodium hydroxide; In methanol; ethanol;
DOI:10.1080/15257779408012169