2,4-dinitro-6-(methoxycarbonyl)phenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside

Base Information

• Chemical Name: 2,4-dinitro-6-(methoxycarbonyl)phenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside
• CAS No.: 367946-88-1
• Molecular Formula: C₄₂H₄₀N₂O₁₂
• Molecular Weight: 764.786
• Mol file: 367946-88-1.mol

Synonyms:2,4-dinitro-6-(methoxycarbonyl)phenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside

Chemical Property of 2,4-dinitro-6-(methoxycarbonyl)phenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,4-dinitro-6-(methoxycarbonyl)phenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside

There total 4 articles about 2,4-dinitro-6-(methoxycarbonyl)phenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

2,3,4,6-tetra-O-benzyl-D-mannopyranose (4132-28-9,4291-69-4,6386-24-9,6564-72-3,59531-24-7,69257-52-9,78184-89-1,78609-16-2,78609-17-3,78609-18-4,96553-53-6,104111-61-7,131347-08-5) + methyl 2-fluoro-3,5-dinitrobenzoic ester (367946-80-3) → 2,4-dinitro-6-(methoxycarbonyl)phenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside (367946-88-1)

Guidance literature:

With dmap; lithium carbonate; In dichloromethane; for 0.5h;

DOI:10.1021/jo0057654

Reference yield:

2-fluoro-3,5-dinitrobenzoic acid chloride (393-74-8) → 2,4-dinitro-6-(methoxycarbonyl)phenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside (367946-88-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 7.10 g / 0.5 h

2: 75 percent / DMAP; Li₂CO₃ / CH₂Cl₂ / 0.5 h

With dmap; lithium carbonate; In dichloromethane;

DOI:10.1021/jo0057654

Reference yield:

2-fluoro-3,5-dinitrobenzoic acid (445-65-8) → 2,4-dinitro-6-(methoxycarbonyl)phenyl 2,3,4,6-tetra-O-benzyl-α-D-mannopyranoside (367946-88-1)

Guidance literature:

Multi-step reaction with 3 steps

1: (COCl)2 / dimethylformamide; CH₂Cl₂ / 1 h / 25 °C

2: 7.10 g / 0.5 h

3: 75 percent / DMAP; Li₂CO₃ / CH₂Cl₂ / 0.5 h

With dmap; oxalyl dichloride; lithium carbonate; In dichloromethane; N,N-dimethyl-formamide;

DOI:10.1021/jo0057654

upstream raw materials:

2,3,4,6-tetra-O-benzyl-D-mannopyranose

methyl 2-fluoro-3,5-dinitrobenzoic ester

2-fluoro-3,5-dinitrobenzoic acid chloride

2-fluoro-3,5-dinitrobenzoic acid