3,6-dibromocyclohexa-3,5-diene-1,2-diamine

Base Information

• Chemical Name: 3,6-dibromocyclohexa-3,5-diene-1,2-diamine
• CAS No.: 1241375-11-0
• Molecular Formula: C₆H₈Br₂N₂
• Molecular Weight: 267.951
• Mol file: 1241375-11-0.mol

Synonyms:3,6-dibromocyclohexa-3,5-diene-1,2-diamine

Chemical Property of 3,6-dibromocyclohexa-3,5-diene-1,2-diamine

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3,6-dibromocyclohexa-3,5-diene-1,2-diamine

There total 3 articles about 3,6-dibromocyclohexa-3,5-diene-1,2-diamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

4,7-dibromobenzo[c][1,2,5]thiadiazole (15155-41-6) → 3,6-dibromocyclohexa-3,5-diene-1,2-diamine (1241375-11-0)

Guidance literature:

With sodium tetrahydroborate; In ethanol; at 30 ℃; for 48h;

DOI:10.1039/c7ra01449j

Reference yield:

benzo[1,2,5]thiadiazole (273-13-2,22706-22-5) → 3,6-dibromocyclohexa-3,5-diene-1,2-diamine (1241375-11-0)

Guidance literature:

Multi-step reaction with 2 steps

1: bromine; hydrogen bromide

2: sodium tetrahydroborate / ethanol / 0 °C

With sodium tetrahydroborate; hydrogen bromide; bromine; In ethanol;

DOI:10.1039/c6tc00197a

Reference yield:

1,2-diamino-benzene (95-54-5) → 3,6-dibromocyclohexa-3,5-diene-1,2-diamine (1241375-11-0)

Guidance literature:

Multi-step reaction with 3 steps

1.1: triethylamine / dichloromethane / 0.17 h / 20 °C

1.2: 4 h / Reflux

2.1: bromine; hydrogen bromide / 6 h / Reflux

3.1: sodium hydride / ethanol / 12 h / 0 - 20 °C / Inert atmosphere

With hydrogen bromide; bromine; sodium hydride; triethylamine; In ethanol; dichloromethane;

DOI:10.1039/c8cc01748d

upstream raw materials:

4,7-dibromobenzo[c][1,2,5]thiadiazole

benzo[1,2,5]thiadiazole

1,2-diamino-benzene

Downstream raw materials:

5-(8-bromo-2,3-di-phenylquinoxalin-5-yl)thiophene-2-carbaldehyde

5,8-dibromo-2,3-diphenylquinoxaline