3-(1-benzenesulfonyl-1H-indol-3-yl)-4-chloro-1-phenyl-1H-pyrrole-2,5-dione

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Chemical Name:3-(1-benzenesulfonyl-1H-indol-3-yl)-4-chloro-1-phenyl-1H-pyrrole-2,5-dione
CAS No.:1178894-31-9
Molecular Formula:C₂₄H₁₅ClN₂O₄S
Molecular Weight:462.913
Hs Code.:

Synonyms:3-(1-benzenesulfonyl-1H-indol-3-yl)-4-chloro-1-phenyl-1H-pyrrole-2,5-dione

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Chemical Property of 3-(1-benzenesulfonyl-1H-indol-3-yl)-4-chloro-1-phenyl-1H-pyrrole-2,5-dione

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Technology Process of 3-(1-benzenesulfonyl-1H-indol-3-yl)-4-chloro-1-phenyl-1H-pyrrole-2,5-dione

There total 1 articles about 3-(1-benzenesulfonyl-1H-indol-3-yl)-4-chloro-1-phenyl-1H-pyrrole-2,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.7%

: 959418-00-9
4-chloro-3-(1H-indol-3-yl)-1-phenyl-1H-pyrrole-2,5-dione

: 98-09-9
benzenesulfonyl chloride

: 1178894-31-9
3-(1-benzenesulfonyl-1H-indol-3-yl)-4-chloro-1-phenyl-1H-pyrrole-2,5-dione

Guidance literature:: 4-chloro-3-(1H-indol-3-yl)-1-phenyl-1H-pyrrole-2,5-dione; With sodium hydride; In tetrahydrofuran; at -40 ℃; for 0.333333h; Cooling;

benzenesulfonyl chloride; In tetrahydrofuran; for 1h; Cooling;
DOI:10.2174/1570180811310050003

Reference yield: 44.5%

: 272-49-1
1H-pyrrolo[3,2-b]pyridine

: 1178894-31-9
3-(1-benzenesulfonyl-1H-indol-3-yl)-4-chloro-1-phenyl-1H-pyrrole-2,5-dione

: 1178894-37-5
3-(1-benzenesulfonyl-1H-indol-3-yl)-1-phenyl-4-(1H-pyrrolo[3,2-b]pyridin-1-yl)-1H-pyrrole-2,5-dione

Guidance literature:: 1H-pyrrolo[3,2-b]pyridine; With lithium diisopropyl amide; In tetrahydrofuran; at -10 ℃; for 0.5h; Inert atmosphere;

3-(1-benzenesulfonyl-1H-indol-3-yl)-4-chloro-1-phenyl-1H-pyrrole-2,5-dione; In tetrahydrofuran; at -20 ℃; Inert atmosphere;
DOI:10.1016/j.bmc.2009.05.031