Technology Process of C11H8ClNO2
There total 1 articles about C11H8ClNO2 which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
cis,trans-2,5-dimethoxytetrahydrofuran; 2-amino-3-chlorobenzoic acid;
With
4-chlorpyridine hydrochloride;
In
1,4-dioxane;
Reflux;
With
water;
In
1,4-dioxane;
- Guidance literature:
-
With
ammonium hydroxide; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
at 20 ℃;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; benzotriazol-1-ol; ammonium hydroxide / N,N-dimethyl-formamide / 20 °C
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 3 h / Inert atmosphere; Cooling with ice; Reflux
2.2: 20 °C / Inert atmosphere
With
ammonium hydroxide; lithium aluminium tetrahydride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
tetrahydrofuran; N,N-dimethyl-formamide;