ethyl 2-[2-(1-(4-methoxyphenylamino)-4,5-dimethyl-1H-imidazol-2-ylthio)acetamido]thiazole-4-carboxylate

Base Information

Chemical Name:ethyl 2-[2-(1-(4-methoxyphenylamino)-4,5-dimethyl-1H-imidazol-2-ylthio)acetamido]thiazole-4-carboxylate
CAS No.:1418010-83-9
Molecular Formula:C₂₀H₂₃N₅O₄S₂
Molecular Weight:461.566
Hs Code.:

Synonyms:ethyl 2-[2-(1-(4-methoxyphenylamino)-4,5-dimethyl-1H-imidazol-2-ylthio)acetamido]thiazole-4-carboxylate

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Chemical Property of ethyl 2-[2-(1-(4-methoxyphenylamino)-4,5-dimethyl-1H-imidazol-2-ylthio)acetamido]thiazole-4-carboxylate

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Technology Process of ethyl 2-[2-(1-(4-methoxyphenylamino)-4,5-dimethyl-1H-imidazol-2-ylthio)acetamido]thiazole-4-carboxylate

There total 3 articles about ethyl 2-[2-(1-(4-methoxyphenylamino)-4,5-dimethyl-1H-imidazol-2-ylthio)acetamido]thiazole-4-carboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

: 19745-93-8
2-(2-chloro-acetylamino)-thiazole-4-carboxylic acid ethyl ester

: 1418010-97-5
C₁₂H₁₅N₃OS

: 1418010-83-9
ethyl 2-[2-(1-(4-methoxyphenylamino)-4,5-dimethyl-1H-imidazol-2-ylthio)acetamido]thiazole-4-carboxylate

Guidance literature:: With potassium carbonate; In acetone; at 20 ℃; for 24h;
DOI:10.1007/s00044-012-0411-5

Reference yield:

: 3471-32-7
4-Methoxyphenylhydrazine

: 1418010-83-9
ethyl 2-[2-(1-(4-methoxyphenylamino)-4,5-dimethyl-1H-imidazol-2-ylthio)acetamido]thiazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid / 20 °C

2: potassium carbonate / acetone / 24 h / 20 °C

With potassium carbonate; acetic acid; In acetone;
DOI:10.1007/s00044-012-0411-5

Reference yield:

: 5398-36-7
2-aminothiazole-4-carboxylate

: 1418010-83-9
ethyl 2-[2-(1-(4-methoxyphenylamino)-4,5-dimethyl-1H-imidazol-2-ylthio)acetamido]thiazole-4-carboxylate

Guidance literature:: Multi-step reaction with 2 steps

1: triethylamine / tetrahydrofuran / 20 °C

2: potassium carbonate / acetone / 24 h / 20 °C

With potassium carbonate; triethylamine; In tetrahydrofuran; acetone;
DOI:10.1007/s00044-012-0411-5