potassium 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate

Base Information

Chemical Name:potassium 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate
CAS No.:1350551-16-4
Molecular Formula:C₂₁H₂₁F₂N₂O₃*K
Molecular Weight:426.504
Hs Code.:

Synonyms:potassium 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate

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Chemical Property of potassium 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate

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Technology Process of potassium 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate

There total 2 articles about potassium 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

: 922366-36-7
methyl 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate

: 1350551-16-4
potassium 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate

Guidance literature:: With potassium hydroxide; In methanol;
DOI:10.1021/jm200383j

Reference yield:

: 27469-60-9
1-(4-fluorophenyl)methyl-piperazine

: 1350551-16-4
potassium 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate

Guidance literature:: Multi-step reaction with 2 steps

1: O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine / dichloromethane

2: potassium hydroxide / methanol

With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; potassium hydroxide; In methanol; dichloromethane;
DOI:10.1021/jm200383j

Reference yield:

: 496-12-8
isoindoline

: 1350551-16-4
potassium 4-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-oxobutanoate

: 1326218-02-3
1-(4-(bis(4-fluorophenyl)methyl)piperazin-1-yl)-4-(isoindolin-2-yl)butane-1,4-dione

Guidance literature:: With O-(benzotriazol-1-yl)-N,N,N',N'-tetramethyluronium tetrafluoroborate; triethylamine; In dichloromethane;
DOI:10.1021/jm200383j