4,4-Dichloro-3,5-diphenyl-4,5-dihydro-5-isoxazolol

Base Information Edit

Chemical Name:4,4-Dichloro-3,5-diphenyl-4,5-dihydro-5-isoxazolol
CAS No.:79344-05-1
Molecular Formula:C₁₅H₁₁Cl₂NO₂
Molecular Weight:308.164
Hs Code.:
ChEMBL ID:CHEMBL1414419
DSSTox Substance ID:DTXSID001333256
Mol file:79344-05-1.mol

Synonyms:79344-05-1;4,4-dichloro-3,5-diphenyl-4,5-dihydro-5-isoxazolol;4,4-dichloro-3,5-diphenyl-1,2-oxazol-5-ol;4,4-dichloro-3,5-diphenyl-4,5-dihydro-1,2-oxazol-5-ol;MLS001195629;CHEMBL1414419;FTRQKNOKNVOAOI-UHFFFAOYSA-N;DTXSID001333256;HMS2873G15;AKOS005109681;RS-0048;SMR000550796;3,5-di-phenyl-4,4-dichloro-5-hydroxyisoxazoline;4,4-Dichloro-3,5-diphenyl-4,5-dihydroisoxazol-5-ol

Suppliers and Price of 4,4-Dichloro-3,5-diphenyl-4,5-dihydro-5-isoxazolol

Supply Marketing:Edit

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 3 raw suppliers

Chemical Property of 4,4-Dichloro-3,5-diphenyl-4,5-dihydro-5-isoxazolol Edit

Chemical Property:

XLogP3:3.8
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:307.0166840
Heavy Atom Count:20
Complexity:387

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)C2=NOC(C2(Cl)Cl)(C3=CC=CC=C3)O

Technology Process of 4,4-Dichloro-3,5-diphenyl-4,5-dihydro-5-isoxazolol

There total 2 articles about 4,4-Dichloro-3,5-diphenyl-4,5-dihydro-5-isoxazolol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 35.0%

: 79344-04-0
2,2-dichloro-1,3-diphenylpropane-1,3-dione

: 79344-05-1
3,5-diphenyl-4,4-dichloro-5-hydroxy-Δ²-isoxazoline

Guidance literature:: With hydroxylamine hydrochloride; In water; acetic acid; at 50 - 60 ℃; for 8h;

Reference yield:

: 4571-27-1
2-chloro-1,3-diphenyl-propane-1,3-dione

: 79344-05-1
3,5-diphenyl-4,4-dichloro-5-hydroxy-Δ²-isoxazoline

Guidance literature:: Multi-step reaction with 2 steps

1: 45.8 percent / SO₂Cl₂, azodiisobutyronitrile / 5.5 h / Heating

2: 35 percent / NH₂OH*HCl / acetic acid; H₂O / 8 h / 50 - 60 °C

With sulfuryl dichloride; 2,2'-azobis(isobutyronitrile); hydroxylamine hydrochloride; In water; acetic acid;