1-(7-methoxy-benzofuran-2-yl)-ethylamine

Base Information

• Chemical Name: 1-(7-methoxy-benzofuran-2-yl)-ethylamine
• CAS No.: 147724-85-4
• Molecular Formula: C₁₁H₁₃NO₂
• Molecular Weight: 191.23
• Mol file: 147724-85-4.mol

Synonyms:1-(7-methoxy-benzofuran-2-yl)-ethylamine

Chemical Property of 1-(7-methoxy-benzofuran-2-yl)-ethylamine

Chemical Property:

• Boiling Point: 298.8±25.0 °C(Predicted)
• Density: 1.141±0.06 g/cm3(Predicted)

Purity/Quality:

99% ^*data from raw suppliers

1-(7-methoxy-1-benzofuran-2-yl)ethan-1-amine ^*data from reagent suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1-(7-methoxy-benzofuran-2-yl)-ethylamine

There total 3 articles about 1-(7-methoxy-benzofuran-2-yl)-ethylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(7-methoxy-benzofuran-2-yl)-ethanone oxime (478248-83-8) → 1-(7-methoxy-benzofuran-2-yl)-ethylamine (147724-85-4)

Guidance literature:

With hydrogenchloride; hydrogen; palladium on activated charcoal; In ethanol; at 26 ℃; for 2h; under 3800.26 Torr;

DOI:10.1039/b312682j

Reference yield:

2-acetyl-7-hydroxybenzofuran (40020-87-9) → 1-(7-methoxy-benzofuran-2-yl)-ethylamine (147724-85-4)

Guidance literature:

Multi-step reaction with 3 steps

1: 61.4 percent / K₂CO₃ / acetone / 2 h / 54 °C

2: 75 percent / hydroxylamine hydrochloride; pyridine / methanol / 1 h / 65 °C

3: HCl; H₂ / Pd/C / ethanol / 2 h / 26 °C / 3800.26 Torr

With pyridine; hydrogenchloride; hydroxylamine hydrochloride; hydrogen; potassium carbonate; palladium on activated charcoal; In methanol; ethanol; acetone;

DOI:10.1039/b312682j

Reference yield:

2-Acetyl-7-methoxybenzofuran (43071-52-9) → 1-(7-methoxy-benzofuran-2-yl)-ethylamine (147724-85-4)

Guidance literature:

Multi-step reaction with 2 steps

1: 75 percent / hydroxylamine hydrochloride; pyridine / methanol / 1 h / 65 °C

2: HCl; H₂ / Pd/C / ethanol / 2 h / 26 °C / 3800.26 Torr

With pyridine; hydrogenchloride; hydroxylamine hydrochloride; hydrogen; palladium on activated charcoal; In methanol; ethanol;

DOI:10.1039/b312682j

upstream raw materials:

1-(7-methoxy-benzofuran-2-yl)-ethanone oxime

2-acetyl-7-hydroxybenzofuran

2-Acetyl-7-methoxybenzofuran