3-Ribofuranosyl-1,2,4-triazole-5-carboxamide

Base Information

Chemical Name:3-Ribofuranosyl-1,2,4-triazole-5-carboxamide
CAS No.:62404-64-2
Molecular Formula:C₈H₁₂N₄O₅
Molecular Weight:244.207
Hs Code.:
ChEMBL ID:CHEMBL3144068

Synonyms:3-beta-D-ribofuranosyl-1,2,4-triazole-5-carboxamide;3-BRTC;3-ribofuranosyl-1,2,4-triazole-5-carboxamide

Suppliers and Price of 3-Ribofuranosyl-1,2,4-triazole-5-carboxamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 5 raw suppliers

Chemical Property of 3-Ribofuranosyl-1,2,4-triazole-5-carboxamide

Chemical Property:

Vapor Pressure:6.83E-20mmHg at 25°C
Boiling Point:688.3°C at 760 mmHg
Flash Point:370.1°C
PSA：154.58000
Density:1.744g/cm³
LogP:-2.24210
XLogP3:-2.6
Hydrogen Bond Donor Count:5
Hydrogen Bond Acceptor Count:7
Rotatable Bond Count:3
Exact Mass:244.08076950
Heavy Atom Count:17
Complexity:304

Purity/Quality:: 99% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:C(C1C(C(C(O1)C2=NC(=NN2)C(=O)N)O)O)O
Isomeric SMILES:C([C@@H]1[C@H]([C@H]([C@@H](O1)C2=NC(=NN2)C(=O)N)O)O)O

Technology Process of 3-Ribofuranosyl-1,2,4-triazole-5-carboxamide

There total 7 articles about 3-Ribofuranosyl-1,2,4-triazole-5-carboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 62.2%

: 62404-63-1
2-<(aminocarbonyl)carbonyl>-1-(β-D-ribofuranosyliminomethyl)hydrazine

: 62404-64-2
ribavirin

Guidance literature:: at 135 ℃; for 0.25h; under 0.1 Torr;
DOI:10.1021/jo01290a002

Reference yield:

: 69244-21-9
5-(tri-O-benzoyl-β-D-ribofuranosyl)-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester

: 62404-64-2
ribavirin

Guidance literature:: With ammonia; In methanol;

Reference yield:

: 69244-20-8
(2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid

: 62404-64-2
ribavirin

Guidance literature:: Multi-step reaction with 3 steps

1: 2-methoxy-ethanol

2: NaOMe / methanol

3: NH₃ / methanol

With ammonia; sodium methylate; In methanol; 2-methoxy-ethanol;