(2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid

Base Information

• Chemical Name: (2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid
• CAS No.: 69244-20-8
• Molecular Formula: C₂₉H₂₇NO₇S*ClH
• Molecular Weight: 570.063

Synonyms:(2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid

Chemical Property of (2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of (2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid

There total 2 articles about (2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 25.0%

2,3,5-tri-O-benzoyl-β-D-ribofuranosyl-1-carbonitrile (23316-67-8) + ethanethiol (75-08-1) → (2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid (69244-20-8)

Guidance literature:

With hydrogenchloride; In diethyl ether; at 0 ℃;

DOI:10.1016/S0008-6215(00)90269-6

Reference yield:

→ (2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid (69244-20-8)

Guidance literature:

2,3,5-Tri-D-benzoyl-β-D-ribofuranosylcyanid, Aethanthiol;

Reference yield: 41.0%

(2',3',5'-Tri-O-benzoyl-β-D-ribofuranosyl)-ethylthioformimid-hydrochlorid (69244-20-8) + 5,6-diamino-1,3-dimethyluracil monotosylate hydrate → N1-(6-amino-1,3-dimethyluracil-5-yl)-5-O-(benzyloxymethyl)-2-furamidine hydrochloride (108967-23-3)

Guidance literature:

In pyridine; for 0.0833333h; Heating;

DOI:10.1016/S0008-6215(00)90269-6

upstream raw materials:

2,3,5-tri-O-benzoyl-β-D-ribofuranosyl-1-carbonitrile

ethanethiol

Downstream raw materials:

5-(tri-O-benzoyl-β-D-ribofuranosyl)-1H-[1,2,4]triazole-3-carboxylic acid ethyl ester

N¹-(6-amino-1,3-dimethyluracil-5-yl)-5-O-(benzyloxymethyl)-2-furamidine hydrochloride

ribavirin

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