2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile

Base Information

Chemical Name:2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile
CAS No.:856014-44-3
Molecular Formula:C₂₀H₁₉BrN₆O
Molecular Weight:439.314
Hs Code.:

Synonyms:2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile

Suppliers and Price of 2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile

There total 3 articles about 2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 75.0%

: 265107-04-8
1-[1-methyl-2-(4-morpholinyl)-1H-imidazol-4-yl]ethanone

: 2972-74-9
2-(3-bromobenzylidene)malononitrile

: 856014-44-3
2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile

Guidance literature:: With ammonium acetate; In 1,2-dichloro-ethane; Heating;
DOI:10.1016/j.bmc.2005.03.023

Reference yield:

: 88723-37-9
1-[2-(4-morpholinyl)-1H-imidazol-4-yl]ethanone

: 856014-44-3
2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile

Guidance literature:: Multi-step reaction with 2 steps

1: 49 percent / NaH / tetrahydrofuran; dimethylformamide / 1.5 h / 20 °C

2: 75 percent / ammonium acetate / 1,2-dichloro-ethane / Heating

With ammonium acetate; sodium hydride; In tetrahydrofuran; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2005.03.023

Reference yield:

: 87005-17-2
5-acetyl-2-amino-oxazole

: 856014-44-3
2-amino-4-(3-bromophenyl)-6-[1-methyl-2-(morpholin-4-yl)-1H-imidazol-4-yl]nicotinonitrile

Guidance literature:: Multi-step reaction with 3 steps

1: 33 percent / H₂O / Heating

2: 49 percent / NaH / tetrahydrofuran; dimethylformamide / 1.5 h / 20 °C

3: 75 percent / ammonium acetate / 1,2-dichloro-ethane / Heating

With ammonium acetate; sodium hydride; In tetrahydrofuran; water; 1,2-dichloro-ethane; N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2005.03.023