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Propanedinitrile, also known as [(3-bromophenyl)methylene]-, is a chemical compound with the molecular formula C9H6BrN2. It is a derivative of malononitrile, featuring a 3-bromophenyl group attached to the methylene bridge. Propanedinitrile, [(3-bromophenyl)methylene]- is characterized by its aromatic ring structure and the presence of a bromine atom, which imparts unique chemical properties. It is used in the synthesis of various organic compounds and pharmaceuticals, particularly those requiring a halogenated aromatic moiety. The compound's reactivity and stability make it a valuable intermediate in organic synthesis, with potential applications in the development of new drugs and other specialty chemicals.

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  • 2972-74-9 Structure
  • Basic information

    1. Product Name: Propanedinitrile, [(3-bromophenyl)methylene]-
    2. Synonyms: 3-bromobenzylidenemalononitrile;m-bromobenzylidenemalononitrile;
    3. CAS NO:2972-74-9
    4. Molecular Formula: C10H5BrN2
    5. Molecular Weight: 233.067
    6. EINECS: N/A
    7. Product Categories: N/A
    8. Mol File: 2972-74-9.mol
  • Chemical Properties

    1. Melting Point: N/A
    2. Boiling Point: N/A
    3. Flash Point: N/A
    4. Appearance: N/A
    5. Density: N/A
    6. Refractive Index: N/A
    7. Storage Temp.: N/A
    8. Solubility: N/A
    9. CAS DataBase Reference: Propanedinitrile, [(3-bromophenyl)methylene]-(CAS DataBase Reference)
    10. NIST Chemistry Reference: Propanedinitrile, [(3-bromophenyl)methylene]-(2972-74-9)
    11. EPA Substance Registry System: Propanedinitrile, [(3-bromophenyl)methylene]-(2972-74-9)
  • Safety Data

    1. Hazard Codes: N/A
    2. Statements: N/A
    3. Safety Statements: N/A
    4. WGK Germany:
    5. RTECS:
    6. HazardClass: N/A
    7. PackingGroup: N/A
    8. Hazardous Substances Data: 2972-74-9(Hazardous Substances Data)

2972-74-9 Usage

Check Digit Verification of cas no

The CAS Registry Mumber 2972-74-9 includes 7 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 4 digits, 2,9,7 and 2 respectively; the second part has 2 digits, 7 and 4 respectively.
Calculate Digit Verification of CAS Registry Number 2972-74:
(6*2)+(5*9)+(4*7)+(3*2)+(2*7)+(1*4)=109
109 % 10 = 9
So 2972-74-9 is a valid CAS Registry Number.

2972-74-9SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name (3-Bromobenzylidene)malononitrile

1.2 Other means of identification

Product number -
Other names 3-bromobenzylidenemalononitrile

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:2972-74-9 SDS

2972-74-9Relevant articles and documents

Ultrasonic synthesis, characterization, and antibacterial evaluation of novel heterocycles containing hexahydroquinoline and pyrrole moieties

Vazirimehr, Simin,Davoodnia, Abolghasem,Nakhaei-Moghaddam, Mahboobeh,Tavakoli-Hoseini, Niloofar

, p. 65 - 70 (2017)

Condensation reaction of dimedone with 2-amino-1-methyl-4,5-diphenyl-1H-pyrrole-3-carbonitrile in ethanol containing a catalytic amount of p-toluenesulfonic acid (TsOH) afforded 2-(5,5-dimethyl-3-oxocyclohex-1-enylamino)-1-methyl-4,5-diphenyl-1H-pyrrole-3

Stereoselective multicomponent synthesis of (2RS,6SR)-2,6-diaryl-3,3,5,5-tetracyanopiperidines

Vereshchagin,Karpenko,Elinson,Gorbunov,Anisina, Yu. E.,Egorov

, p. 1534 - 1537 (2018)

Multicomponent reaction between alkylidenemalononitriles, formaldehyde, and ammonium acetate upon reflux in alcohols gives stereoselectively 2,6-diaryl-3,3,5,5-tetracyanopiperidines in 65—92% yields. In this process, ammonium acetate acts as both a cataly

Introduction of succinimide as a green and sustainable organo-catalyst for the synthesis of arylidene malononitrile and tetrahydrobenzo[b] pyran derivatives

Hassanzadeh, Fariba,Shirini, Farhad,Mamaghani, Manouchehr,Daneshvar, Nader

, p. 155 - 163 (2021/03/23)

Aim and Objective: In this work, we tried to introduce a non-toxic and stable organic compound named succinimide as a green and efficient organo-catalyst for the promotion of the synthesis of arylidene malononitrile and tetrahydrobenzo[b]pyran derivatives

Development of an efficient, one-pot, multicomponent protocol for synthesis of 8-hydroxy-4-phenyl-1,2-dihydroquinoline derivatives

Tabassum, Rukhsana,Ashfaq, Muhammad,Oku, Hiroyuki

, p. 534 - 547 (2020/12/04)

A one-pot quick and efficient multicomponent reaction has been developed for the synthesis of a new series of functionalized 8-hydroxy-4-phenyl-1,2-dihydroquinoline derivatives using 30 mol% ammonium acetate in ethanol as solvent. This economical protocol

Nickel?alkyne?functionalized metal?organic frameworks: An efficient and reusable catalyst

Chen, Huixin,Cheng, Hua,Li, Jilin,Li, Wei,Liao, Shengyun,Liu, Xin,Ning, Liangmin,Shao, Liming,Tang, Siyuan

, (2021/06/15)

Electron-donating groups in the robust MOF motif are able to provide an excellent catalytic platform, therefore obtaining site-isolated metal sites. In this study, the terminal alkyne is firstly introduced into UiO-66-type metal-organic frameworks (UiO-66-alkyne). Herein, to further study the application potential of this material, a covalently bonded nickel catalyst based on the alkynyl-tagged UiO-66-alkyne has been prepared and afforded us unprecedented highly dispersed and highly efficient catalytic active species. Meanwhile, this nickel-contained catalyst method for joining metals provided an alternative pathway regarding catalyst designing. With UiO-66-alkyne-Ni, the heterogeneous transformation of homogeneous catalysts is realized. Using benzaldehyde and malononitrile as starting materials, we were able to catalyze the Knoevenagel condensation within 45 min under room temperature with yield (> 99 %). Moreover, the recovery rate of the UiO-66-alkyne-Ni also outperformed previous MOFs in both small-scale and gram-level reactions, which shows UiO-66-alkyne-Ni is a potential contributor to the subsequent industrialization.

Phosphine-Catalyzed (4 + 2) Annulation of δ-Sulfonamido-Substituted Enones with 1,1-Dicyanoalkenes: Synthesis of Piperidine Derivatives

Liu, Min,Zhou, Leijie,Shi, Wangyu,Hu, Yimin,Liao, Jianning,Duan, Zeqing,Wang, Wei,Wu, Yongjun,Zheng, Bing,Guo, Hongchao

supporting information, p. 7703 - 7707 (2021/10/20)

The δ-sulfonamido-substituted enones were employed as phosphine acceptor in phosphine-catalyzed (4 + 2) annulation of 1,1-dicyanoalkenes. They served as a four-membered synthon to react with 1,1-dicyanoalkenes under mild reaction conditions, producing pip

Cascade reaction synthesis method of 2-(phenylmethylene)malononitrile or derivative thereof

-

Paragraph 0063-0067, (2020/03/12)

The invention discloses a cascade reaction synthesis method of 2-(phenylmethylene)malononitrile or a derivative thereof. According to the invention, a dendritic acid-alkali catalyst based on cross-linked polystyrene is synthesized, and 2-(phenylmethylene) malononitrile or a derivative thereof is synthesized in batches by successfully applying a cascade reaction into fluid chemistry, so that the method of the invention has advantages of substantially reduced, yield increase and no separation process of a catalyst and a product compared with the traditional test tube reaction.

Highly Active Bisamino Functionalized Zr(IV)-UiO-67 Metal-Organic Framework for Cascade Catalysis

Das, Aniruddha,Anbu, Nagaraj,Mostakim,Dhakshinamoorthy, Amarajothi,Biswas, Shyam

supporting information, p. 2830 - 2834 (2020/07/04)

This work reports the synthesis and characterization of Zr(IV)-based UiO-67-(NH2)2 (called 1) metal-organic framework. Activated 1 (named 1') was shown to be an efficient tandem catalyst in the conversion of benzaldehydedimethyl acet

Structure-induced Lewis-base Ga4B2O9 and its superior performance in Knoevenagel condensation reaction

Cong, Rihong,Gao, Wenliang,Jiang, Pengfei,Wang, Duo,Yang, Tao,Yang, Yao

, (2020/05/01)

Solid Lewis-base catalysis is important in the production of fine chemicals. A Lewis-base Ga4B2O9 was synthesized by high temperature solid state reactions. It exhibited a high yield (90 %) and a high stability in Knoevena

Supramolecular polymeric aggregation behavior and its impact on catalytic properties of imidazolium based hydrophilic ionic liquids

Muhammad, Shoaib,Javed, Muhammad Naveed,Ali, Firdous Imran,Bari, Ahmed,Hashmi, Imran Ali

, (2020/01/21)

Ionic Liquids (ILs) self-assemble to form supramolecular polymeric clusters/aggregates. The aggregation behavior of ILs influences its activity in the organic synthesis. However, the precise role of ILs in organic reactions is still unknown. It is, therefore, important to comprehend the supramolecular polymeric aggregation behavior of ILs. We are exploring the supramolecular polymeric aggregation behavior of ILs using Electrospray Ionization Mass Spectrometry (ESI-MS). We have synthesized four hydrophilic ILs (1–4) and investigated their aggregation behavior and its impact on catalytic activity in Carbon-Carbon bond formation (Knoevenagel and Claisen-Schmidt condensation). Here, we show that the aggregation behavior of ILs depends on the type and nature of cation and anion. ESI-MS (?ve) spectra reveals two different type of aggregation i.e. [CnAn+1]? & [A2 + H+]?. We have found that catalytic activity increases with increased [CnAn+1]? supramolecular aggregation. Consequently, highest yield of products obtained in ILs which show decreased anion-anion aggregation [A2 + H+]? abundance in ESI-MS. We anticipate our results to be a starting point for the establishment of desired ILs for organic synthesis.

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