C₁₅H₁₆FN

Base Information

• Chemical Name: C₁₅H₁₆FN
• CAS No.: 1019558-76-9
• Molecular Formula: C₁₅H₁₆FN
• Molecular Weight: 229.297
• Mol file: 1019558-76-9.mol

Synonyms:C₁₅H₁₆FN

Chemical Property of C₁₅H₁₆FN

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₅H₁₆FN

There total 2 articles about C₁₅H₁₆FN which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C15H14FN → C15H16FN (1019558-76-9)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In Isopropyl acetate; at 24 ℃; for 24h; under 11251.1 Torr;

DOI:10.1002/adsc.201100250

Reference yield:

2'-Fluoroacetophenone (445-27-2) + benzylamine (100-46-9) → C15H16FN (1019558-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1: titanium(IV) isopropylate / Isopropyl acetate / 0.5 h

2: 5%-palladium/activated carbon; hydrogen / Isopropyl acetate / 24 h / 24 °C / 11251.1 Torr

With titanium(IV) isopropylate; 5%-palladium/activated carbon; hydrogen; In Isopropyl acetate;

DOI:10.1002/adsc.201100250

Reference yield:

C15H16FN (1019558-76-9) → 1-(2-fluorophenyl)ethanamine (74788-44-6,185545-90-8)

Guidance literature:

With 5%-palladium/activated carbon; hydrogen; In Isopropyl acetate; at 55 ℃; for 24h;

DOI:10.1002/adsc.201100250

upstream raw materials:

2'-Fluoroacetophenone

benzylamine

Downstream raw materials:

2,2,2-trifluoro-N-(1-(2-(fluoro)phenyl)ethyl)acetamide

1-(2-fluorophenyl)ethanamine

Refernces