C₁₅H₁₂F₃N₃

Base Information

• Chemical Name: C₁₅H₁₂F₃N₃
• CAS No.: 1181455-16-2
• Molecular Formula: C₁₅H₁₂F₃N₃
• Molecular Weight: 291.276
• Mol file: 1181455-16-2.mol

Synonyms:C₁₅H₁₂F₃N₃

Chemical Property of C₁₅H₁₂F₃N₃

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

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Technology Process of C₁₅H₁₂F₃N₃

There total 1 articles about C₁₅H₁₂F₃N₃ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C15H14F3N (1181455-67-3) → C15H12F3N3 (1181455-16-2)

Guidance literature:

C₁₅H₁₄F₃N; With acetic acid; sodium nitrite; In water; at 0 ℃; for 2h; Inert atmosphere;

With sodium azide; In water; at 0 - 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/ol901317j

Reference yield: 83.0%

C15H12F3N3 (1181455-16-2) → C15H12F3N (595548-60-0)

Guidance literature:

With (Et4N)2[(Co(II)(μ2-N(o-PhNC(O)(i-Pr)-κN)2))2]; In N,N-dimethyl-formamide; toluene; at 110 ℃; for 48h; Molecular sieve;

DOI:10.1039/c5sc01162k

Reference yield:

C15H12F3N3 (1181455-16-2) → C15H12F3N (595548-60-0) + C15H14F3N (1181455-67-3) + 2-[4-(trifluoromethyl)phenyl]-1H-indole (243971-02-0)

Guidance literature:

C₁₅H₁₂F₃N₃; With (1,5-cyclooctadiene)(methoxy)iridium(I) dimer; In benzene; at 25 ℃; for 16h; Inert atmosphere;

With silica gel;

DOI:10.1021/ol901317j

upstream raw materials:

C₁₅H₁₄F₃N

Downstream raw materials:

C₁₅H₁₂F₃N

C₁₅H₁₄F₃N

2-[4-(trifluoromethyl)phenyl]-1H-indole