Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester

Base Information

Chemical Name:Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester
CAS No.:75511-64-7
Molecular Formula:C₁₅H₂₂O₆S
Molecular Weight:330.402
Hs Code.:

Synonyms:Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester

Suppliers and Price of Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester

There total 5 articles about Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 68136-78-7
2,5-Anhydro-4,6-dideoxy-L-lyxo-hexose Dimethyl Acetal

: 98-59-9
p-toluenesulfonyl chloride

: 75511-64-7
Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester

Guidance literature:: In pyridine; at 0 ℃; for 72h;
DOI:10.1021/ja00545a018

Reference yield:

: 39022-34-9
3,6-di-O-p-tolylsulfonyl-2,5-anhydro-L-idofuranose dimethylacetal

: 75511-64-7
Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester

Guidance literature:: Multi-step reaction with 4 steps

1: 93 percent / sodium hydride / tetrahydrofuran / 25 °C

2: dimethylformamide / Heating

3: 96 percent / W-4 Raney nickel / tetrahydrofuran / 25 °C

4: pyridine / 0 °C

With pyridine; W-4 Raney nickel; sodium hydride; In tetrahydrofuran; N,N-dimethyl-formamide;
DOI:10.1021/ja00522a095

Reference yield:

: 67492-43-7
2,5:3,4-dianhydro-L-talose dimethyl acetal p-toluenesulfonate

: 75511-64-7
Toluene-4-sulfonic acid (2R,3R,5S)-2-dimethoxymethyl-5-methyl-tetrahydro-furan-3-yl ester

Guidance literature:: Multi-step reaction with 3 steps

1: 92 percent / sodium borohydride / dimethylformamide / 80 °C

2: 96 percent / Raney Ni / tetrahydrofuran / 2 h / Ambient temperature

3: 98 percent / pyridine / 72 h / 0 °C

With sodium tetrahydroborate; nickel; In tetrahydrofuran; pyridine; N,N-dimethyl-formamide;
DOI:10.1021/ja00545a018