2,3-diamino-N₂-(2-(4-((4-methylpiperazin-1-yl)methyl)phenoxy)ethyl)quinoxaline

Base Information

Chemical Name:2,3-diamino-N₂-(2-(4-((4-methylpiperazin-1-yl)methyl)phenoxy)ethyl)quinoxaline
CAS No.:1350648-13-3
Molecular Formula:C₂₂H₂₈N₆O
Molecular Weight:392.504
Hs Code.:

2,3-diamino-N<sub>2</sub>-(2-(4-((4-methylpiperazin-1-yl)methyl)phenoxy)ethyl)quinoxaline

Synonyms:2,3-diamino-N₂-(2-(4-((4-methylpiperazin-1-yl)methyl)phenoxy)ethyl)quinoxaline

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Chemical Property of 2,3-diamino-N₂-(2-(4-((4-methylpiperazin-1-yl)methyl)phenoxy)ethyl)quinoxaline

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Technology Process of 2,3-diamino-N₂-(2-(4-((4-methylpiperazin-1-yl)methyl)phenoxy)ethyl)quinoxaline

There total 2 articles about 2,3-diamino-N₂-(2-(4-((4-methylpiperazin-1-yl)methyl)phenoxy)ethyl)quinoxaline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 6640-47-7
2,3-diaminoquinoxaline

: C₁₄H₂₁BrN₂O

: 1350648-13-3
2,3-diamino-N₂-(2-(4-((4-methylpiperazin-1-yl)methyl)phenoxy)ethyl)quinoxaline

Guidance literature:: 2,3-diaminoquinoxaline; With sodium hydride; In N,N-dimethyl-formamide; at 20 ℃; for 0.5h;

C₁₄H₂₁BrN₂O; In N,N-dimethyl-formamide; at 35 ℃; for 0.5h;
DOI:10.1016/j.bmc.2011.09.061

Reference yield:

: 80166-00-3
4-[(4-methylpiperazin-1-yl)methyl]phenol

: 1350648-13-3
2,3-diamino-N₂-(2-(4-((4-methylpiperazin-1-yl)methyl)phenoxy)ethyl)quinoxaline

Guidance literature:: Multi-step reaction with 2 steps

1.1: tetrabutylammomium bromide; sodium hydroxide / 4 h / Reflux

2.1: sodium hydride / N,N-dimethyl-formamide / 0.5 h / 20 °C

2.2: 0.5 h / 35 °C

With tetrabutylammomium bromide; sodium hydride; sodium hydroxide; In N,N-dimethyl-formamide;
DOI:10.1016/j.bmc.2011.09.061