Technology Process of 1-(4-methoxyphenyl)-4,4-dimethyl-2,3-dioxabicyclo[3.2.1]octane
There total 5 articles about 1-(4-methoxyphenyl)-4,4-dimethyl-2,3-dioxabicyclo[3.2.1]octane which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
oxygen; 2,4,6-tri-(p-methoxyphenyl) pyrylium tetrafluoroborate;
In
1,2-dichloro-ethane;
at -10 ℃;
for 3.5h;
under 760.051 Torr;
Solvent;
Temperature;
Inert atmosphere;
UV-irradiation;
DOI:10.3762/bjoc.10.128
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: magnesium; ethylene dibromide / diethyl ether / 2 h / 0 °C / Inert atmosphere
1.2: 18 h / 0 - 20 °C / Inert atmosphere
2.1: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / 16 h / -78 - 20 °C
3.1: potassium tert-butylate / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
3.2: 16 h / 0 - 20 °C / Inert atmosphere
4.1: 2,4,6-tri-(p-methoxyphenyl) pyrylium tetrafluoroborate; oxygen / 1,2-dichloro-ethane / 3.5 h / -10 °C / 760.05 Torr / Inert atmosphere; UV-irradiation
With
oxalyl dichloride; potassium tert-butylate; oxygen; 2,4,6-tri-(p-methoxyphenyl) pyrylium tetrafluoroborate; magnesium; dimethyl sulfoxide; ethylene dibromide; triethylamine;
In
tetrahydrofuran; diethyl ether; dichloromethane; 1,2-dichloro-ethane;
1.1: |Grignard Reaction / 1.2: |Grignard Reaction / 2.1: |Swern Oxidation / 3.1: |Wittig Olefination / 3.2: |Wittig Olefination;
DOI:10.3762/bjoc.10.128
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: oxalyl dichloride; dimethyl sulfoxide; triethylamine / dichloromethane / 16 h / -78 - 20 °C
2.1: potassium tert-butylate / tetrahydrofuran / 1 h / 0 °C / Inert atmosphere
2.2: 16 h / 0 - 20 °C / Inert atmosphere
3.1: 2,4,6-tri-(p-methoxyphenyl) pyrylium tetrafluoroborate; oxygen / 1,2-dichloro-ethane / 3.5 h / -10 °C / 760.05 Torr / Inert atmosphere; UV-irradiation
With
oxalyl dichloride; potassium tert-butylate; oxygen; 2,4,6-tri-(p-methoxyphenyl) pyrylium tetrafluoroborate; dimethyl sulfoxide; triethylamine;
In
tetrahydrofuran; dichloromethane; 1,2-dichloro-ethane;
1.1: |Swern Oxidation / 2.1: |Wittig Olefination / 2.2: |Wittig Olefination;
DOI:10.3762/bjoc.10.128
