p-chlorophenylglyoxal thiosemicarbazone

Base Information

• Chemical Name: p-chlorophenylglyoxal thiosemicarbazone
• CAS No.: 109047-06-5
• Molecular Formula: C₉H₈ClN₃OS
• Molecular Weight: 241.701
• Mol file: 109047-06-5.mol

Synonyms:p-chlorophenylglyoxal thiosemicarbazone

Chemical Property of p-chlorophenylglyoxal thiosemicarbazone

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of p-chlorophenylglyoxal thiosemicarbazone

There total 2 articles about p-chlorophenylglyoxal thiosemicarbazone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

thiosemicarbazide (79-19-6) + 4-chlorophenylglyoxal (4998-15-6) → p-chlorophenylglyoxal thiosemicarbazone (109047-06-5)

Guidance literature:

In ethanol; for 0.333333h; Reflux;

DOI:10.1016/j.tet.2021.132158

Reference yield:

→ p-chlorophenylglyoxal thiosemicarbazone (109047-06-5)

Guidance literature:

4-Chlor-phenylglyoxal, Thiosemicarbazid/W. (Eg.);

Reference yield:

p-chlorophenylglyoxal thiosemicarbazone (109047-06-5) + 4-(p-cyanophenyl)-4-bromo-1-butyne (121598-73-0) → 2-(p-cyanophenyl)-6-(p-chlorophenyl)-2,3-dihydrothieno[2,3-b]pyridine

Guidance literature:

p-chlorophenylglyoxal thiosemicarbazone; With sodium hydride; In ethanol; mineral oil; at 20 ℃; for 0.25h;

4-(p-cyanophenyl)-4-bromo-1-butyne; In ethanol; mineral oil; for 1h; Reflux;

In chlorobenzene; at 132 ℃; for 6h; Reflux;

DOI:10.1016/j.tet.2021.132158

upstream raw materials:

thiosemicarbazide

4-chlorophenylglyoxal

Downstream raw materials:

5-(4-chloro-phenyl)-2H-[1,2,4]triazine-3-thione

5-(4-chloro-phenyl)-3-piperazino-[1,2,4]triazine