2-Acetyl-3-methyl-5-methoxyphenol

Base Information

Chemical Name:2-Acetyl-3-methyl-5-methoxyphenol
CAS No.:6540-66-5
Molecular Formula:C10H12 O3
Molecular Weight:180.203
Hs Code.:2914509090
Mol file:6540-66-5.mol

Synonyms:Acetophenone,2'-hydroxy-4'-methoxy-6'-methyl- (8CI);2'-Hydroxy-4'-methoxy-6'-methylacetophenone; 2'-Hydroxy-6'-methyl-4'-methoxyacetophenone;Acetoevernone

Suppliers and Price of 2-Acetyl-3-methyl-5-methoxyphenol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 4 raw suppliers

Chemical Property of 2-Acetyl-3-methyl-5-methoxyphenol

Chemical Property:

Melting Point:79 °C
Boiling Point:321.8±37.0 °C(Predicted)
PKA:9.90±0.15(Predicted)
PSA：46.53000
Density:1.128±0.06 g/cm3(Predicted)
LogP:1.91180

Purity/Quality:: 95% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Technology Process of 2-Acetyl-3-methyl-5-methoxyphenol

There total 11 articles about 2-Acetyl-3-methyl-5-methoxyphenol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 703-29-7
1-(2,4-dihydroxy-6-methylphenyl)ethanone

: 74-88-4
methyl iodide

: 6540-66-5
1-(2-hydroxy-4-methoxy-6-methylphenyl)ethanone

Guidance literature:: With potassium carbonate; In acetone; for 3h; Reflux;
DOI:10.1016/j.tetlet.2009.01.086

Reference yield: 46.0%

: 3209-13-0
O-methylorcinol

: 108-24-7
acetic anhydride

: 6540-66-5
1-(2-hydroxy-4-methoxy-6-methylphenyl)ethanone

: 31405-63-7
1-(2-hydroxy-6-methoxy-4-methylphenyl)ethanone

Guidance literature:: With titanium tetrachloride; In dichloromethane; at 0 - 20 ℃; for 6h;
DOI:10.1071/CH99134

Reference yield:

: 61539-56-8
4,4,4-trimethoxybutan-2-one

: 63446-76-4,63446-77-5,68225-97-8
1-methyl-1,3-bis(trimethylsilyloxy)buta-1,3-diene

: 6540-66-5
1-(2-hydroxy-4-methoxy-6-methylphenyl)ethanone

Guidance literature:: 4,4,4-trimethoxybutan-2-one; 1-methyl-1,3-bis(trimethylsilyloxy)buta-1,3-diene; With titanium tetrachloride; In dichloromethane; at -78 - 20 ℃; for 12h; Inert atmosphere;

With hydrogenchloride; In dichloromethane; water; for 0.166667h; regioselective reaction; Inert atmosphere;
DOI:10.1515/znb-2020-0114