4-(1-Phenyl-1H-1,2,3-triazol-4-yl)aniline

Base Information

Chemical Name:4-(1-Phenyl-1H-1,2,3-triazol-4-yl)aniline
CAS No.:1232432-29-9
Molecular Formula:C₁₄H₁₂N₄
Molecular Weight:236.276
Hs Code.:
DSSTox Substance ID:DTXSID10704648
Wikidata:Q82637125

Synonyms:1232432-29-9;SCHEMBL11904306;DTXSID10704648;FT-0762458;4-(1-Phenyl-1H-1,2,3-triazol-4-yl)aniline

Suppliers and Price of 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)aniline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)aniline

Chemical Property:

XLogP3:2.3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:2
Exact Mass:236.106196400
Heavy Atom Count:18
Complexity:257

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC=C(C=C1)N2C=C(N=N2)C3=CC=C(C=C3)N

Technology Process of 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)aniline

There total 8 articles about 4-(1-Phenyl-1H-1,2,3-triazol-4-yl)aniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1232432-29-9
4-(4-aminophenyl)-1-phenyl-1H-[1,2,3]triazole

Guidance literature:: With copper catalyst supported on SBA-15 molecular sieve functionalized with propylthioacetic acid; In water; at 50 ℃; for 6h; Inert atmosphere; Sealed tube;

Reference yield: 74.0%

: 14235-81-5
4-Ethynylaniline

: 622-37-7
Phenyl azide

: 1232432-29-9
4-(4-aminophenyl)-1-phenyl-1H-[1,2,3]triazole

Guidance literature:: With copper(ll) sulfate pentahydrate; sodium L-ascorbate; In water; tert-butyl alcohol; at 60 ℃; for 17h;
DOI:10.1016/j.bmc.2011.11.041

Reference yield:

: 555-16-8
4-nitrobenzaldehdye

: 1232432-29-9
4-(4-aminophenyl)-1-phenyl-1H-[1,2,3]triazole

Guidance literature:: Multi-step reaction with 6 steps

1: pyridine; piperidine / isopropyl alcohol / Heating

2: bromine; acetic acid / dichloromethane / 20 °C

3: triethylamine / N,N-dimethyl-formamide / 0.03 h / 35 °C / Microwave irradiation

4: 1,8-diazabicyclo[5.4.0]undec-7-ene / 0.17 h / 35 °C / Microwave irradiation

5: hydrazine hydrate; palladium 10% on activated carbon / ethanol / Heating

6: copper(ll) sulfate pentahydrate; ascorbic acid / N,N-dimethyl-formamide; water / 50 °C

With piperidine; pyridine; copper(ll) sulfate pentahydrate; palladium 10% on activated carbon; bromine; hydrazine hydrate; acetic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; triethylamine; ascorbic acid; In ethanol; dichloromethane; water; N,N-dimethyl-formamide; isopropyl alcohol; 1: |Knoevenagel-Doebner-Stobbe Reaction;
DOI:10.1016/j.ejmech.2019.03.047