Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2,5-dimethyl-phenyl]-acetic acid methyl ester

Base Information

• Chemical Name: Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2,5-dimethyl-phenyl]-acetic acid methyl ester
• CAS No.: 21004-07-9
• Molecular Formula: C₁₈H₁₄N₄O₄
• Molecular Weight: 350.334
• Mol file: 21004-07-9.mol

Synonyms:Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2,5-dimethyl-phenyl]-acetic acid methyl ester

Chemical Property of Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2,5-dimethyl-phenyl]-acetic acid methyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
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MSDS Files:

Useful:

Technology Process of Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2,5-dimethyl-phenyl]-acetic acid methyl ester

There total 3 articles about Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2,5-dimethyl-phenyl]-acetic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,5-bis(chloromethyl)-p-xylene (6298-72-2) → Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2,5-dimethyl-phenyl]-acetic acid methyl ester (21004-07-9)

Guidance literature:

Multi-step reaction with 2 steps

2: 1.) NaOCH₃

With sodium methylate;

Reference yield:

carbonic acid dimethyl ester (616-38-6) + 2,5-dimethyl-1,4-phenylenediacetonitrile (1134-68-5) + cyanogen chloride (506-77-4) → Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2,5-dimethyl-phenyl]-acetic acid methyl ester (21004-07-9)

Guidance literature:

Multistep reaction; (i) NaOMe, (ii) /BRN= 969190/;

DOI:10.1021/jo00909a019

Reference yield:

para-xylene (106-42-3) → Dicyano-[4-(dicyano-methoxycarbonyl-methyl)-2,5-dimethyl-phenyl]-acetic acid methyl ester (21004-07-9)

Guidance literature:

Multi-step reaction with 3 steps

1: HCl

3: 1.) NaOCH₃

With hydrogenchloride; sodium methylate;

upstream raw materials:

carbonic acid dimethyl ester

2,5-dimethyl-1,4-phenylenediacetonitrile

cyanogen chloride

para-xylene

Downstream raw materials:

2-(4-Dicyanomethyl-2,5-dimethyl-phenyl)-malononitrile

2,5-dimethyl-7,7,8,8-tetracyanoquinodimethane