2,5-Bis(chloromethyl)-p-xylene

Base Information

• Chemical Name: 2,5-Bis(chloromethyl)-p-xylene
• CAS No.: 6298-72-2
• Molecular Formula: C10H12 Cl2
• Molecular Weight: 203.111
• Hs Code.: 2903999090
• European Community (EC) Number: 228-575-5
• NSC Number: 41890
• UNII: H6FDY6Z9VM
• DSSTox Substance ID: DTXSID4064210
• Nikkaji Number: J206.867B
• Wikidata: Q81991339
• Mol file: 6298-72-2.mol

Synonyms:2,5-Bis(chloromethyl)-p-xylene;6298-72-2;1,4-Bis(chloromethyl)-2,5-dimethylbenzene;Benzene, 1,4-bis(chloromethyl)-2,5-dimethyl-;2,5-Di(Chloromethyl)-p-xylene;alpha(1),alpha(4)-Dichlorodurene;EINECS 228-575-5;NSC 41890;NSC-41890;.alpha.(1),.alpha.(4)-Dichlorodurene;2,5-bis-(Chloromethyl)-p-xylene;NSC41890;H6FDY6Z9VM;YSZC366;SCHEMBL442987;C10H12Cl2;2,5-Bis(chloromethyl)p-xylene;2,5-Bis(chloromethyl-p-xylene;DTXSID4064210;MFCD00013682;AKOS003614502;2,5dimethyl 1,4bis-chloromethyl benzene;BS-52037;1,4-di(chloromethyl)-2,5-dimethylbenzene;1,4-Dimethyl-2,5-di(chloromethyl)benzene;1,4-Dimethyl-2,5-bis(chloromethyl)benzene;2,5 dimethyl 1,4 bis-chloromethyl benzene;Benzene,4-bis(chloromethyl)-2,5-dimethyl-;LS-185171;FT-0610256;E70422

Chemical Property of 2,5-Bis(chloromethyl)-p-xylene

Chemical Property:

• Vapor Pressure: 0.0034mmHg at 25°C
• Melting Point: 132-134°C
• Boiling Point: 291.5°C at 760 mmHg
• Flash Point: 142.2°C
• PSA: 0.00000
• Density: 1.145g/cm³
• LogP: 3.78100
• XLogP3: 3.4
• Hydrogen Bond Donor Count: 0
• Hydrogen Bond Acceptor Count: 0
• Rotatable Bond Count: 2
• Exact Mass: 202.0316058
• Heavy Atom Count: 12
• Complexity: 120

Purity/Quality:

99.9% ^*data from raw suppliers

2,5-BIS(CHLOROMETHYL)-P-XYLENE 95.00% ^*data from reagent suppliers

Safty Information:

• Statements: 36/37/38
• Safety Statements: 26-36/37/39

MSDS Files:

SDS file from LookChem

Useful:

• Canonical SMILES: CC1=CC(=C(C=C1CCl)C)CCl

Technology Process of 2,5-Bis(chloromethyl)-p-xylene

There total 9 articles about 2,5-Bis(chloromethyl)-p-xylene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 94.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + para-xylene (106-42-3) → 2,5-bis(chloromethyl)-p-xylene (6298-72-2)

Guidance literature:

With hydrogenchloride; In water; methyl cyclohexane; at 60 ℃; for 8h;

DOI:10.1007/BF03246210

Reference yield: 49.0%

formaldehyd (50-00-0,30525-89-4,61233-19-0) + para-xylene (106-42-3) → 2,5-bis(chloromethyl)-p-xylene (6298-72-2) + 2,5-dimethylbenzyl chloride (824-45-3)

Guidance literature:

With hydrogenchloride; 1-ethyl-3-methylimidazolium hexafluorophosphate; at 70 ℃; for 5h; Ionic liquid;

DOI:10.4067/S0717-97072013000400063

Reference yield:

para-xylene (106-42-3) → 2,5-bis(chloromethyl)-p-xylene (6298-72-2)

Guidance literature:

DOI:10.1016/S0176-1617(00)80110-8

upstream raw materials:

formaldehyd

para-xylene

1,3,5-Trioxan

Octanethiol

Downstream raw materials:

tetraethyl ((2,5-dimethyl-1,4-phenylene)bis(methylene))bis(phosphonate)

2,5-dimethyl-p-phenylenedimethylene-1,1'-bis(tetrahydrothiophen-1-ium) dichloride

tetramethyl[(2,5-dimethylbenzene-1,4-diyl)dimethanediyl]bis(phosphonate)

1,4-bis(bromomethyl)-2,5-bis(dimethoxyphosphorylmethyl)benzene