(R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal

Base Information

• Chemical Name: (R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal
• CAS No.: 573970-34-0
• Molecular Formula: C₂₀H₂₇NO₂
• Molecular Weight: 313.44
• Mol file: 573970-34-0.mol

Synonyms:(R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal

Chemical Property of (R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal

There total 1 articles about (R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

dimethoxyacetaldehyde (51673-84-8) + (R,R)-N,N-bis-(1-phenylethyl)amine (10024-74-5,21003-56-5,21003-57-6,23294-41-9,42287-48-9,56210-72-1) → (R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal (573970-34-0) + (R,R)-(-)-bis(α-methylbenzyl)aminoacetic acid methyl ester

Guidance literature:

With sodium tris(acetoxy)borohydride; acetic acid; In dichloromethane; at 20 ℃; for 72h;

DOI:10.1039/b210116e

Reference yield: 87.0%

ethylmagnesium bromide (925-90-6) + (R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal (573970-34-0) → ((R,R)-(-)-bis(α-methylbenzyl)amino)-2-methoxybutane

Guidance literature:

(R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal; With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -78 ℃; for 0.5h;

ethylmagnesium bromide; In dichloromethane; toluene; at -78 - 20 ℃; for 16h; Further stages.;

DOI:10.1039/b210116e

Reference yield: 86.0%

4-cyclohexen-1-ylmorpholine (670-80-4) + (R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal (573970-34-0) → 2-[2-((R,R)-(-)-bis(α-methylbenzyl)amino)-1-methoxyethyl]cyclohexanone

Guidance literature:

(R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde dimethyl acetal; With trimethylsilyl trifluoromethanesulfonate; In dichloromethane; at -78 ℃; for 0.5h;

4-cyclohexen-1-ylmorpholine; In dichloromethane; at -78 - 20 ℃; for 2.5h; Further stages.;

DOI:10.1039/b210116e

upstream raw materials:

dimethoxyacetaldehyde

(R,R)-N,N-bis-(1-phenylethyl)amine

Downstream raw materials:

3-(2-indolyl)indole

(R,R)-(-)-bis(α-methylbenzyl)aminoacetaldehyde diisopropyl acetal