N,2-dimethyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazole-3-carboxamide hydrochloride

Base Information

Chemical Name:N,2-dimethyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazole-3-carboxamide hydrochloride
CAS No.:1029643-58-0
Molecular Formula:C₂₄H₃₀N₄O*ClH
Molecular Weight:426.989
Hs Code.:

Synonyms:N,2-dimethyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazole-3-carboxamide hydrochloride

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of N,2-dimethyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazole-3-carboxamide hydrochloride

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Technology Process of N,2-dimethyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazole-3-carboxamide hydrochloride

There total 2 articles about N,2-dimethyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazole-3-carboxamide hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

: 1029643-56-8
2-methyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazol-3-carboxamide hydrochloride

: 74-88-4
methyl iodide

: 1029643-58-0
N,2-dimethyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazole-3-carboxamide hydrochloride

Guidance literature:: 2-methyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazol-3-carboxamide hydrochloride; With sodium hydride; In tetrahydrofuran; mineral oil; at 25 ℃; for 1h;

methyl iodide; In tetrahydrofuran; mineral oil; at 25 ℃; for 48h;

With hydrogenchloride; In ethanol; ethyl acetate; at 25 ℃; for 3h;
DOI:10.1002/cmdc.201800199

Reference yield:

: 1029644-01-6
N,2-dimethyl-N-((1-(2-phenylethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide

: 74-88-4
methyl iodide

: 1029643-58-0
N,2-dimethyl-N-{[1-(2-phenylethyl)piperidin-4-yl]methyl}-2H-indazole-3-carboxamide hydrochloride

Guidance literature:: N,2-dimethyl-N-((1-(2-phenylethyl)piperidin-4-yl)methyl)-2H-indazole-3-carboxamide; With hydrogenchloride; In ethanol; ethyl acetate; at 20 ℃; for 3h;

methyl iodide; In tetrahydrofuran; at 20 ℃; for 48h;