4-{4-[Bis(methanesulfonyl)amino]phenyl}butylcarbamic acid tert-butyl ester

Base Information

• Chemical Name: 4-{4-[Bis(methanesulfonyl)amino]phenyl}butylcarbamic acid tert-butyl ester
• CAS No.: 742102-27-8
• Molecular Formula: C₁₇H₂₈N₂O₆S₂
• Molecular Weight: 420.551
• Mol file: 742102-27-8.mol

Synonyms:4-{4-[Bis(methanesulfonyl)amino]phenyl}butylcarbamic acid tert-butyl ester

Chemical Property of 4-{4-[Bis(methanesulfonyl)amino]phenyl}butylcarbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 4-{4-[Bis(methanesulfonyl)amino]phenyl}butylcarbamic acid tert-butyl ester

There total 2 articles about 4-{4-[Bis(methanesulfonyl)amino]phenyl}butylcarbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

[4-(4-aminophenyl)butyl]carbamic acid tert-butyl ester (742102-26-7) + methanesulfonyl chloride (124-63-0) → 4-{4-[Bis(methanesulfonyl)amino]phenyl}butylcarbamic acid tert-butyl ester (742102-27-8)

Guidance literature:

With dmap; triethylamine; In tetrahydrofuran;

Reference yield:

[4-(4-Nitrophenyl)but-3-ynyl]carbamic acid tert-butyl ester (742102-25-6) → 4-{4-[Bis(methanesulfonyl)amino]phenyl}butylcarbamic acid tert-butyl ester (742102-27-8)

Guidance literature:

Multi-step reaction with 2 steps

1: palladium / ethanol

2: dmap; triethylamine / tetrahydrofuran

With dmap; triethylamine; palladium; In tetrahydrofuran; ethanol;

upstream raw materials:

[4-(4-aminophenyl)butyl]carbamic acid tert-butyl ester

methanesulfonyl chloride

[4-(4-Nitrophenyl)but-3-ynyl]carbamic acid tert-butyl ester