Technology Process of C43H54N6O9
There total 12 articles about C43H54N6O9 which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Boc-GFGFP-OH;
With
4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride;
In
N,N-dimethyl-formamide;
at 0 ℃;
for 0.166667h;
2-amino-3-phenylpropyl acetate hydrochloride;
With
4-methyl-morpholine;
In
N,N-dimethyl-formamide;
at 20 ℃;
pH=8;
DOI:10.1111/j.1747-0285.2012.01331.x
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: 4-methyl-morpholine; isobutyl chloroformate / acetonitrile / 0.17 h / -15 - 0 °C
1.2: 20 °C
2.1: pyridine / 1 h / 20 °C
3.1: hydrogenchloride / 1,4-dioxane / 1.5 h
4.1: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.17 h / 0 °C
4.2: 20 °C / pH 8
With
4-methyl-morpholine; pyridine; hydrogenchloride; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; isobutyl chloroformate;
In
1,4-dioxane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1111/j.1747-0285.2012.01331.x
- Guidance literature:
-
Multi-step reaction with 6 steps
1.1: hydrogenchloride / 1,4-dioxane
2.1: 4-methyl-morpholine; isobutyl chloroformate
3.1: Alkaline conditions
4.1: 4-methyl-morpholine; isobutyl chloroformate
5.1: palladium 10% on activated carbon; ammonium formate / methanol / 0.5 h / 20 °C
6.1: 4-methyl-morpholine; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride / N,N-dimethyl-formamide / 0.17 h / 0 °C
6.2: 20 °C / pH 8
With
4-methyl-morpholine; hydrogenchloride; palladium 10% on activated carbon; ammonium formate; benzotriazol-1-ol; 1-ethyl-(3-(3-dimethylamino)propyl)-carbodiimide hydrochloride; isobutyl chloroformate;
In
1,4-dioxane; methanol; N,N-dimethyl-formamide;
DOI:10.1111/j.1747-0285.2012.01331.x
