C₁₅H₂₀O₄

Base Information

• Chemical Name: C₁₅H₂₀O₄
• CAS No.: 1346619-90-6
• Molecular Formula: C₁₅H₂₀O₄
• Molecular Weight: 264.321
• Mol file: 1346619-90-6.mol

Synonyms:C₁₅H₂₀O₄

Chemical Property of C₁₅H₂₀O₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₅H₂₀O₄

There total 3 articles about C₁₅H₂₀O₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

Trimethyl orthoacetate (1445-45-0) + C12H16O3 (1346619-89-3) → C15H20O4 (1346619-90-6)

Guidance literature:

With propionic acid; In toluene; at 150 ℃; for 12h; Inert atmosphere;

DOI:10.1021/ol202881q

Reference yield:

C13H16O4 (1346619-88-2) → C15H20O4 (1346619-90-6)

Guidance literature:

Multi-step reaction with 2 steps

1: diisobutylaluminium hydride / dichloromethane / -78 °C / Inert atmosphere

2: propionic acid / toluene / 12 h / 150 °C / Inert atmosphere

With diisobutylaluminium hydride; propionic acid; In dichloromethane; toluene; 2: Johnson-Claisen rearrangement;

DOI:10.1021/ol202881q

Reference yield:

3,5-dimethoxybenzaldehdye (7311-34-4) → C15H20O4 (1346619-90-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride / tetrahydrofuran / 13 h / Inert atmosphere

2: diisobutylaluminium hydride / dichloromethane / -78 °C / Inert atmosphere

3: propionic acid / toluene / 12 h / 150 °C / Inert atmosphere

With diisobutylaluminium hydride; propionic acid; 1,8-diazabicyclo[5.4.0]undec-7-ene; lithium chloride; In tetrahydrofuran; dichloromethane; toluene; 3: Johnson-Claisen rearrangement;

DOI:10.1021/ol202881q

upstream raw materials:

Trimethyl orthoacetate

C₁₂H₁₆O₃

C₁₃H₁₆O₄

3,5-dimethoxybenzaldehdye

Downstream raw materials:

C₁₆H₂₀O₆

3-(3,5-dimethoxyphenyl)4-methylpent-4-enoic acid