ethyl (5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoate

Base Information

• Chemical Name: ethyl (5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoate
• CAS No.: 115798-06-6
• Molecular Formula: C₂₄H₄₀O₇S
• Molecular Weight: 472.643
• Mol file: 115798-06-6.mol

Synonyms:ethyl (5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoate

Chemical Property of ethyl (5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of ethyl (5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoate

There total 2 articles about ethyl (5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

2,4,6-triisopropylphenylsulfonyl chloride (6553-96-4) + 5,6,7-Trihydroxy-heptanoic acid ethyl ester (79308-41-1) → 5,6-Dihydroxy-7-(2,4,6-triisopropyl-benzenesulfonyloxy)-heptanoic acid ethyl ester (115798-00-0,115798-06-6)

Guidance literature:

With pyridine;

DOI:10.1016/0008-6215(90)84073-4

Reference yield:

2,4,6-triisopropylphenylsulfonyl chloride (6553-96-4) + (5R,6S)-5,6,7-Trihydroxy-heptanoic acid ethyl ester (79308-41-1) → ethyl (5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoate (115798-06-6)

Guidance literature:

With pyridine; for 24h; Ambient temperature;

DOI:10.1016/0008-6215(90)84073-4

Reference yield: 78.0%

ethyl (5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoate (115798-06-6) → (5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoic-1,5-lactone (115798-07-7)

Guidance literature:

With hydrogenchloride; In tetrahydrofuran; for 10h; Heating;

DOI:10.1016/0008-6215(90)84073-4

upstream raw materials:

2,4,6-triisopropylphenylsulfonyl chloride

5,6,7-Trihydroxy-heptanoic acid ethyl ester

(5R,6S)-5,6,7-Trihydroxy-heptanoic acid ethyl ester

Downstream raw materials:

2,4,6-Triisopropyl-benzenesulfonic acid 2-hydroxy-2-(6-oxo-tetrahydro-pyran-2-yl)-ethyl ester

3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid 1-(6-oxo-tetrahydro-pyran-2-yl)-2-(2,4,6-triisopropyl-benzenesulfonyloxy)-ethyl ester

(5R,6S)-5,6-dihydroxy-7-(triisopropylbenzenesulfonyloxy)heptanoic-1,5-lactone

(S)-3,3,3-Trifluoro-2-methoxy-2-phenyl-propionic acid (S)-1-((R)-6-oxo-tetrahydro-pyran-2-yl)-2-(2,4,6-triisopropyl-benzenesulfonyloxy)-ethyl ester