1-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOL-1

Base Information

• Chemical Name: 1-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOL-1
• CAS No.: 618-97-3
• Molecular Formula: C₁₀H₁₁F₃O
• Molecular Weight: 204.192
• Hs Code.: 2906299090
• Mol file: 618-97-3.mol

Synonyms:Benzylalcohol, a-ethyl-m-(trifluoromethyl)-(8CI); 1-(3-Trifluoromethylphenyl)-1-propanol

Chemical Property of 1-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOL-1

Chemical Property:

• Vapor Pressure: 0.0883mmHg at 25°C
• Refractive Index: 1.4582
• Boiling Point: 88-91/5mm
• PKA: 14.24±0.20(Predicted)
• Flash Point: 96.9°C
• PSA: 20.23000
• Density: 1.197
• LogP: 3.14880

Purity/Quality:

97% ^*data from raw suppliers

1-[3-(Trifluoromethyl)phenyl]propan-1-ol ^*data from reagent suppliers

Safty Information:

• Pictogram(s): Xi
• Hazard Codes: Xi

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of 1-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOL-1

There total 15 articles about 1-[3-(TRIFLUOROMETHYL)PHENYL]PROPANOL-1 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

3-(trifluoromethyl)propiophenone (1533-03-5) → 1-<3-(trifluoromethyl)phenyl>propan-1-ol (618-97-3,575433-48-6)

Guidance literature:

With sodium tetrahydroborate; In methanol; at 20 ℃;

DOI:10.1039/c6gc01981a

Reference yield: 81.0%

1-<3-(trifluoromethyl)phenyl>prop-2-en-1-ol (154309-48-5) → 1-<3-(trifluoromethyl)phenyl>propan-1-ol (618-97-3,575433-48-6)

Guidance literature:

With hydrogen; platinum oxyde; In ethanol; at 20 ℃; for 24h; under 750.06 Torr;

Reference yield: 72.0%

→ 1-<3-(trifluoromethyl)phenyl>propan-1-ol (618-97-3,575433-48-6)

Guidance literature:

upstream raw materials:

3-(trifluoromethyl)phenylmagnesium bromide

propionaldehyde

1-<3-(trifluoromethyl)phenyl>prop-2-en-1-ol

1-(meta-trifluoromethylphenyl)-1,2-propanediol

Downstream raw materials:

3-(trifluoromethyl)propiophenone

3-trifluoromethyl-α-ethyl-benzhydrol

1-[3-(trifluoromethyl)phenyl]propan-1-amine

2-bromo-1-(3-(trifluoromethyl)phenyl)propan-1-one