7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester

Base Information

Chemical Name:7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester
CAS No.:868836-41-3
Molecular Formula:C₃₀H₃₉N₃O₅
Molecular Weight:521.657
Hs Code.:

Synonyms:7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester

Suppliers and Price of 7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

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Technology Process of 7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester

There total 5 articles about 7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.6%

: 868835-87-4
N-{4-[(N,N-dimethylamino)benzyl]butyl}phthalimide

: 41624-92-4
methyl 8-chloro-8-oxooctanoate

: 868836-41-3
7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester

Guidance literature:: With triethylamine; In dichloromethane; at 0 - 20 ℃;
DOI:10.1021/jm0505009

Reference yield: 72.6%

: 868836-41-3
7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester

Guidance literature:

Reference yield:

: 66917-06-4
N-(4-azidobutyl)phthalimide

: 868836-41-3
7-{4-[(phthalimido)amino]butyl}-{N-[4-N,N-(dimethyl)aminobenzyl]carbamoyl}heptanoic acid methyl ester

Guidance literature:: Multi-step reaction with 3 steps

1.1: H₂ / Pd/C / ethanol / 12 h / 1292.87 Torr

2.1: acetic acid / 1,2-dichloro-ethane / 0.33 h / 20 °C

2.2: 0.810 g / NaCNBH₃ / 1,2-dichloro-ethane; methanol / 12 h

3.1: 72.6 percent / triethylamine / CH₂Cl₂ / 0 - 20 °C

With hydrogen; acetic acid; triethylamine; palladium on activated charcoal; In ethanol; dichloromethane; 1,2-dichloro-ethane;
DOI:10.1021/jm0505009