(+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

Base Information

Chemical Name:(+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol
CAS No.:1253197-31-7
Molecular Formula:C₂₆H₂₉NO₄S
Molecular Weight:451.587
Hs Code.:

Synonyms:(+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

Suppliers and Price of (+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

There total 10 articles about (+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

: 1253197-26-0
(+/-)-7-benzyloxy-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

: 19432-96-3
3-(phenylsulfonyl)propyl chloride

: 1253197-31-7
(+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

Guidance literature:: With tetra-(n-butyl)ammonium iodide; potassium carbonate; In acetonitrile; for 72h; Reflux;
DOI:10.1016/j.bmc.2010.09.026

Reference yield:

: 4911-65-3
3-chloropropyl phenyl sulfide

: 1253197-31-7
(+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

Guidance literature:: Multi-step reaction with 2 steps

1.1: acetic acid / 0.5 h / Reflux

1.2: 0.5 h / Reflux

2.1: potassium carbonate; tetra-(n-butyl)ammonium iodide / acetonitrile / 72 h / Reflux

With tetra-(n-butyl)ammonium iodide; potassium carbonate; acetic acid; In acetonitrile;

Reference yield:

: 930-69-8
sodium thiophenolate

: 1253197-31-7
(+/-)-7-benzyloxy-3-[3-(phenylsulfonyl)propyl]-2,3,4,5-tetrahydro-1H-3-benzazepin-1-ol

Guidance literature:: Multi-step reaction with 3 steps

1.1: sodium hydroxide / 1,4-dioxane; water / 24 h / 60 °C

2.1: acetic acid / 0.5 h / Reflux

2.2: 0.5 h / Reflux

3.1: potassium carbonate; tetra-(n-butyl)ammonium iodide / acetonitrile / 72 h / Reflux

With tetra-(n-butyl)ammonium iodide; potassium carbonate; acetic acid; sodium hydroxide; In 1,4-dioxane; water; acetonitrile;