p-tolyl 2-O-tert-butyldiphenylsilyl-3-O-(chloroacetyl)-5,6-O-isopropylidene-1-thio-β-D-galactofuranoside

Base Information

Chemical Name:p-tolyl 2-O-tert-butyldiphenylsilyl-3-O-(chloroacetyl)-5,6-O-isopropylidene-1-thio-β-D-galactofuranoside
CAS No.:1374633-01-8
Molecular Formula:C₃₄H₄₁ClO₆SSi
Molecular Weight:641.3
Hs Code.:

Synonyms:p-tolyl 2-O-tert-butyldiphenylsilyl-3-O-(chloroacetyl)-5,6-O-isopropylidene-1-thio-β-D-galactofuranoside

Suppliers and Price of p-tolyl 2-O-tert-butyldiphenylsilyl-3-O-(chloroacetyl)-5,6-O-isopropylidene-1-thio-β-D-galactofuranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of p-tolyl 2-O-tert-butyldiphenylsilyl-3-O-(chloroacetyl)-5,6-O-isopropylidene-1-thio-β-D-galactofuranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of p-tolyl 2-O-tert-butyldiphenylsilyl-3-O-(chloroacetyl)-5,6-O-isopropylidene-1-thio-β-D-galactofuranoside

There total 2 articles about p-tolyl 2-O-tert-butyldiphenylsilyl-3-O-(chloroacetyl)-5,6-O-isopropylidene-1-thio-β-D-galactofuranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 80.0%

: 1374632-99-1
(2R,3S,4R,5S)-4-(tert-butyldiphenylsilyloxy)-2-((R)-2,2-dimethyl-1,3-dioxolan-4-yl)-5-(p-tolylthio)tetrahydrofuran-3-ol

: 79-04-9
chloroacetyl chloride

: 1374633-01-8
p-tolyl 2-O-tert-butyldiphenylsilyl-3-O-(chloroacetyl)-5,6-O-isopropylidene-1-thio-β-D-galactofuranoside

Guidance literature:: With pyridine; at 0 - 20 ℃; for 5h; Inert atmosphere;
DOI:10.1016/j.tet.2012.03.074

Reference yield:

: 58479-61-1
tert-butylchlorodiphenylsilane

: 1374633-01-8
p-tolyl 2-O-tert-butyldiphenylsilyl-3-O-(chloroacetyl)-5,6-O-isopropylidene-1-thio-β-D-galactofuranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 1H-imidazole; dmap / dichloromethane / 0 - 20 °C / Inert atmosphere

2: pyridine / 5 h / 0 - 20 °C / Inert atmosphere

With pyridine; 1H-imidazole; dmap; In dichloromethane;
DOI:10.1016/j.tet.2012.03.074