C₂₅H₂₈N₆O

Base Information

Chemical Name:C₂₅H₂₈N₆O
CAS No.:1351812-02-6
Molecular Formula:C₂₅H₂₈N₆O
Molecular Weight:428.537
Hs Code.:

C<sub>25</sub>H<sub>28</sub>N<sub>6</sub>O

Synonyms:C₂₅H₂₈N₆O

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Chemical Property of C₂₅H₂₈N₆O

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Technology Process of C₂₅H₂₈N₆O

There total 5 articles about C₂₅H₂₈N₆O which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 55.0%

: 1438841-57-6
N-(3-(5-(cyclohexylamino)-6-(1-methyl-1H-pyrazol-4-yl)-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-3-yl)phenyl)acetamide

: 1351812-02-6
C₂₅H₂₈N₆O

Guidance literature:: With tetrabutyl ammonium fluoride; ethylenediamine; In tetrahydrofuran; for 24h; Reflux;
DOI:10.1021/jm4000215

Reference yield:

: 78887-39-5
3-Acetamidophenylboronic acid

: 1351812-02-6
C₂₅H₂₈N₆O

Guidance literature:: Multi-step reaction with 4 steps

1.1: sodium hydride / N,N-dimethyl-formamide / 0.67 h / 0 - 20 °C

1.2: 3 h / Inert atmosphere; Reflux

2.1: ethanol; iron; ammonium chloride / water / 0.75 h / Reflux

3.1: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 3 h / 20 °C

4.1: tetrabutyl ammonium fluoride; ethylenediamine / tetrahydrofuran / 24 h / Reflux

With ethanol; tetrabutyl ammonium fluoride; sodium tris(acetoxy)borohydride; iron; sodium hydride; ammonium chloride; acetic acid; ethylenediamine; In tetrahydrofuran; dichloromethane; water; N,N-dimethyl-formamide; 1.2: |Suzuki Coupling;
DOI:10.1021/jm4000215

Reference yield:

: 1438841-55-4
N-(3-(6-(1-methyl-1H-pyrazol-4-yl)-5-nitro-1-((2-(trimethylsilyl)ethoxy)methyl)-1H-indazol-3-yl)phenyl)acetamide

: 1351812-02-6
C₂₅H₂₈N₆O

Guidance literature:: Multi-step reaction with 3 steps

1: ethanol; iron; ammonium chloride / water / 0.75 h / Reflux

2: sodium tris(acetoxy)borohydride; acetic acid / dichloromethane / 3 h / 20 °C

3: tetrabutyl ammonium fluoride; ethylenediamine / tetrahydrofuran / 24 h / Reflux

With ethanol; tetrabutyl ammonium fluoride; sodium tris(acetoxy)borohydride; iron; ammonium chloride; acetic acid; ethylenediamine; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/jm4000215