3-(N'-tert-butoxycarbonyl-hydrazino)-2-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-but-2-enoic acid methyl ester

Base Information

• Chemical Name: 3-(N'-tert-butoxycarbonyl-hydrazino)-2-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-but-2-enoic acid methyl ester
• CAS No.: 1027370-87-1
• Molecular Formula: C₂₀H₂₆N₄O₅
• Molecular Weight: 402.45
• Mol file: 1027370-87-1.mol

Synonyms:3-(N'-tert-butoxycarbonyl-hydrazino)-2-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-but-2-enoic acid methyl ester

Chemical Property of 3-(N'-tert-butoxycarbonyl-hydrazino)-2-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-but-2-enoic acid methyl ester

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of 3-(N'-tert-butoxycarbonyl-hydrazino)-2-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-but-2-enoic acid methyl ester

There total 1 articles about 3-(N'-tert-butoxycarbonyl-hydrazino)-2-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-but-2-enoic acid methyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

edaravone (89-25-8) + tert-butyl (3-methoxy-1-methyl-3-oxoprop-1-enyl)diazenecarboxylate → 3-(N'-tert-butoxycarbonyl-hydrazino)-2-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-but-2-enoic acid methyl ester (1027370-87-1)

Guidance literature:

With anion exchanger resin; In tetrahydrofuran; at 20 ℃;

DOI:10.1246/cl.2000.984

Reference yield: 92.0%

3-(N'-tert-butoxycarbonyl-hydrazino)-2-(5-methyl-3-oxo-2-phenyl-2,3-dihydro-1H-pyrazol-4-yl)-but-2-enoic acid methyl ester (1027370-87-1) → C20H24N4O5

Guidance literature:

With selenium(IV) oxide; In tetrahydrofuran; at 20 ℃;

DOI:10.1246/cl.2000.984

upstream raw materials:

edaravone