(1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester

Base Information

Chemical Name:(1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester
CAS No.:1245794-11-9
Molecular Formula:C₂₂H₂₂N₂O₅
Molecular Weight:394.427
Hs Code.:

Synonyms:(1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester

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Chemical Property of (1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester

Chemical Property:

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Technology Process of (1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester

There total 2 articles about (1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1245794-08-4
1-[(4-(3-dimethylaminopropenoyl)-2-methoxy-5-nitrophenoxy)methyl]-N-benzyloxycarbonyl-1-aminocyclopropane

: 1245794-11-9
(1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester

Guidance literature:: 1-[(4-(3-dimethylaminopropenoyl)-2-methoxy-5-nitrophenoxy)methyl]-N-benzyloxycarbonyl-1-aminocyclopropane; With iron; acetic acid; at 80 ℃; for 2h;

With sodium hydrogencarbonate; In ethyl acetate;

Reference yield:

: 6-methoxyquinoline-4,7-diol

: 1-(((benzyloxycarbonyl)amino)cyclopropyl)methylsulfonic acid methyl ester

: 1245794-11-9
(1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester

Guidance literature:: With potassium carbonate; potassium iodide; In acetone; for 40h;

Reference yield: 87.0%

: 1245794-11-9
(1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester

: 1245794-14-2
(1-(((4-chloro-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamic acid benzyl ester

Guidance literature:: (1-(((4-hydroxy-6-methoxyquinolin-7-yl)oxy)methyl)cyclopropyl)carbamate benzyl ester; With trichlorophosphate; at 20 - 85 ℃; Inert atmosphere;

With sodium hydrogencarbonate; In dichloromethane; water; at 20 - 25 ℃; pH=7 - 8;