2-[(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-4,5-dimethoxyaniline

Base Information

Chemical Name:2-[(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-4,5-dimethoxyaniline
CAS No.:59444-58-5
Molecular Formula:C21H28N2O4
Molecular Weight:372.464
Hs Code.:
NSC Number:123401
DSSTox Substance ID:DTXSID00298480

Synonyms:59444-58-5;2-[(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-4,5-dimethoxyaniline;Laudanosine, DL-;NSC123401;DL-6'-Aminolaudanosine;DTXSID00298480;NSC-123401

Suppliers and Price of 2-[(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-4,5-dimethoxyaniline

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 2 raw suppliers

Chemical Property of 2-[(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-4,5-dimethoxyaniline

Chemical Property:

Vapor Pressure:7.64E-11mmHg at 25°C
Boiling Point:518.2°C at 760 mmHg
Flash Point:267.2°C
Density:1.149g/cm³
XLogP3:3
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:6
Exact Mass:372.20490738
Heavy Atom Count:27
Complexity:466

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CN1CCC2=CC(=C(C=C2C1CC3=CC(=C(C=C3N)OC)OC)OC)OC

Technology Process of 2-[(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-4,5-dimethoxyaniline

There total 8 articles about 2-[(6,7-Dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-1-yl)methyl]-4,5-dimethoxyaniline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 133205-93-3
(+/-)-1-(4,5-dimethoxy-2-nitro-benzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline

: 59444-58-5
2-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-4,5-dimethoxy-aniline

Guidance literature:: With hydrogenchloride; tin(ll) chloride;
DOI:10.1016/S0024-3205(00)00557-9

Reference yield:

: 133205-93-3
(R)-1-(4,5-dimethoxy-2-nitro-benzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline

: 59444-58-5
(R)-1-(2-amino-4,5-dimethoxy-benzyl)-6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinoline

Guidance literature:: With hydrogenchloride; tin(ll) chloride;
DOI:10.1016/S0024-3205(00)00557-9

Reference yield:

: 94757-36-5
4,5,3',4'-tetramethoxy-2-vinyl-stilbene

: 59444-58-5
2-(6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydro-isoquinolin-1-ylmethyl)-4,5-dimethoxy-aniline

Guidance literature:: Multi-step reaction with 2 steps

1: acetic acid; concentrated nitric acid

2: SnCl₂; aq.-ethanolic HCl

With hydrogenchloride; nitric acid; acetic acid; tin(ll) chloride;
DOI:10.1016/S0024-3205(00)00557-9