(R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethanamine hydrochloride

Base Information

• Chemical Name: (R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethanamine hydrochloride
• CAS No.: 1198223-10-7
• Molecular Formula: C₁₂H₁₆FNO*ClH
• Molecular Weight: 245.724
• Mol file: 1198223-10-7.mol

Synonyms:(R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethanamine hydrochloride

Chemical Property of (R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethanamine hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethanamine hydrochloride

There total 14 articles about (R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethanamine hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 100.0%

(S)-N-((R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethyl)-2-methylpropane-2-sulfinamide → (R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethanamine hydrochloride (1198223-10-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃; for 0.5h; Inert atmosphere;

DOI:10.1021/jm201628y

Reference yield:

C16H24FNO2S (1309653-57-3) → (R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethanamine hydrochloride (1198223-10-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃; for 0.5h;

Reference yield:

C16H24FNO2S → (R)-1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethanamine hydrochloride (1198223-10-7)

Guidance literature:

With hydrogenchloride; In 1,4-dioxane; methanol; at 20 ℃; for 0.5h;

upstream raw materials:

4-fluoro-3-hydroxybenzoic acid

ethyl 3-hydroxy-4-fluorobenzoate

3-(cyclopropylmethoxy)-4-fluorobenzaldehyde

(3-(cyclopropylmethoxy)-4-fluorophenyl) methanol

Downstream raw materials:

(R)-3-(N-(1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethyl)sulfamoyl)propyl acetate

(R)-N-(1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethyl)-3-hydroxypropane-1-sulfonamide

(R)-N-(1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethyl)-3-(methoxymethoxy)propane-1-sulfonamide

(R)-N-(1-(3-(cyclopropylmethoxy)-4-fluorophenyl)ethyl)-3-((2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)methoxy)propane-1-sulfonamide