[2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester

Base Information

Chemical Name:[2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester
CAS No.:190276-16-5
Molecular Formula:C₃₂H₃₀N₂O₅S
Molecular Weight:554.667
Hs Code.:

[2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-<i>b</i>]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester

Synonyms:[2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester

Suppliers and Price of [2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 1 raw suppliers

Chemical Property of [2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of [2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester

There total 8 articles about [2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 5081-36-7
3-methoxy-4-nitrobenzoic acid

: 190276-16-5
[2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 6 steps

1: thionyl chloride / CHCl₃ / Heating

2: Et₃N / CHCl₃ / 20 °C

3: H₂ / Pd/C

4: Et₃N / 20 °C

5: BBr₃

6: K₂CO₃; KI / acetone; dimethylformamide / 5 h / Heating

With thionyl chloride; hydrogen; boron tribromide; potassium carbonate; triethylamine; potassium iodide; palladium on activated charcoal; In chloroform; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jm030287l

Reference yield:

: 67579-92-4
3-methoxy-4-nitrobenzoic acid chloride

: 190276-16-5
[2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 5 steps

1: Et₃N / CHCl₃ / 20 °C

2: H₂ / Pd/C

3: Et₃N / 20 °C

4: BBr₃

5: K₂CO₃; KI / acetone; dimethylformamide / 5 h / Heating

With hydrogen; boron tribromide; potassium carbonate; triethylamine; potassium iodide; palladium on activated charcoal; In chloroform; N,N-dimethyl-formamide; acetone;
DOI:10.1021/jm030287l

Reference yield:

: 190276-75-6
(3-Methoxy-4-nitro-phenyl)-(5,6,7,8-tetrahydro-thieno[3,2-b]azepin-4-yl)-methanone

: 190276-16-5
[2-[(biphenyl-2-carbonyl)-amino]-5-(5,6,7,8-tetrahydro-thieno[3,2-b]azepine-4-carbonyl)-phenoxy]-acetic acid ethyl ester

Guidance literature:: Multi-step reaction with 4 steps

1: H₂ / Pd/C

2: Et₃N / 20 °C

3: BBr₃

4: K₂CO₃; KI / acetone; dimethylformamide / 5 h / Heating

With hydrogen; boron tribromide; potassium carbonate; triethylamine; potassium iodide; palladium on activated charcoal; In N,N-dimethyl-formamide; acetone;
DOI:10.1021/jm030287l