O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride

Base Information

Chemical Name:O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride
CAS No.:1173035-69-2
Molecular Formula:C₂₇H₃₁NO₇*ClH
Molecular Weight:518.007
Hs Code.:

Synonyms:O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride

Suppliers and Price of O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride

There total 4 articles about O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 71.0%

: 1173184-14-9
trans-4-hydroxy-α,α-diphenyl-L-prolinol hydrochloride

: 96297-73-3
methacrylic acid 2-(3-chlorocarbonylpropionyloxy)ethyl ester

: 1173035-69-2
O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride

Guidance literature:: With trifluoroacetic acid; at 0 - 20 ℃; for 2h; Inert atmosphere;
DOI:10.1039/c3cc46204h

Reference yield:

: 33996-30-4
trans-4-hydroxy-L-proline ethyl ester hydrochloride

: 1173035-69-2
O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride

Guidance literature:: Multi-step reaction with 2 steps

1.1: magnesium / diethyl ether / Inert atmosphere

1.2: 20 °C / Inert atmosphere; Reflux

2.1: trifluoroacetic acid / 2 h / 0 - 20 °C / Inert atmosphere

With magnesium; trifluoroacetic acid; In diethyl ether; 1.1: |Grignard Reaction / 1.2: |Grignard Reaction;
DOI:10.1039/c3cc46204h

Reference yield:

: 51-35-4,30724-02-8
4R-4-hydroxyproline

: 1173035-69-2
O-(2-methacryloyloxyethylsuccinoyl)-trans-4-hydroxy-α,α-di-phenyl-L-prolinol hydrochloride

Guidance literature:: Multi-step reaction with 3 steps

1.1: thionyl chloride / 4 h / 105 °C / Inert atmosphere; Cooling with ice

2.1: magnesium / diethyl ether / Inert atmosphere

2.2: 20 °C / Inert atmosphere; Reflux

3.1: trifluoroacetic acid / 2 h / 0 - 20 °C / Inert atmosphere

With thionyl chloride; magnesium; trifluoroacetic acid; In diethyl ether; 2.1: |Grignard Reaction / 2.2: |Grignard Reaction;
DOI:10.1039/c3cc46204h