diethyl {(4-nitrophenyl)[(4-tolyl)amino]methyl}phosphonate

Base Information

• Chemical Name: diethyl {(4-nitrophenyl)[(4-tolyl)amino]methyl}phosphonate
• CAS No.: 1463490-79-0
• Molecular Formula: C₁₈H₂₃N₂O₅P
• Molecular Weight: 378.365
• Mol file: 1463490-79-0.mol

Synonyms:diethyl {(4-nitrophenyl)[(4-tolyl)amino]methyl}phosphonate

Chemical Property of diethyl {(4-nitrophenyl)[(4-tolyl)amino]methyl}phosphonate

Chemical Property:

Purity/Quality:

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MSDS Files:

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Technology Process of diethyl {(4-nitrophenyl)[(4-tolyl)amino]methyl}phosphonate

There total 4 articles about diethyl {(4-nitrophenyl)[(4-tolyl)amino]methyl}phosphonate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

4-nitrobenzaldehdye (555-16-8) + p-toluidine (106-49-0,12221-03-3) + triethyl phosphite (122-52-1) → diethyl {(4-nitrophenyl)[(4-tolyl)amino]methyl}phosphonate (1463490-79-0)

Guidance literature:

With 1-hydro-4-aza-1-azaniabicyclo-[2.2.2]octane chloride; In methanol; at 20 ℃; for 0.666667h; Green chemistry;

DOI:10.1055/s-0034-1380523

Reference yield: 95.0%

4-nitrobenzaldehdye (555-16-8) + p-toluidine (106-49-0,12221-03-3) + phosphonic acid diethyl ester (762-04-9) → diethyl {(4-nitrophenyl)[(4-tolyl)amino]methyl}phosphonate (1463490-79-0)

Guidance literature:

With nickel(II) sulfate hexahydrate; In neat (no solvent); at 20 ℃; for 0.166667h; Green chemistry;

DOI:10.1007/s11164-015-2283-z

Reference yield: 69.0%

p-methylazidobenzene (2101-86-2) + 4-nitrobenzaldehdye (555-16-8) + phosphonic acid diethyl ester (762-04-9) → diethyl {(4-nitrophenyl)[(4-tolyl)amino]methyl}phosphonate (1463490-79-0)

Guidance literature:

With iodine; iron; In neat (no solvent); at 20 ℃; for 5h;

DOI:10.1055/s-0033-1339377

upstream raw materials:

p-methylazidobenzene

4-nitrobenzaldehdye

phosphonic acid diethyl ester

p-toluidine