1-[4-(Trifluoromethyl)phenyl]propan-2-amine

Base Information

Chemical Name:1-[4-(Trifluoromethyl)phenyl]propan-2-amine
CAS No.:1626-74-0
Molecular Formula:C10H12 F3 N
Molecular Weight:203.207
Hs Code.:2921499090
DSSTox Substance ID:DTXSID00936719
Nikkaji Number:J13.038I
ChEMBL ID:CHEMBL3247894
Mol file:1626-74-0.mol

Synonyms:1626-74-0;1-[4-(trifluoromethyl)phenyl]propan-2-amine;2-Amino-1-[4-(trifluoromethyl)phenyl]propane;1-(4-(TRIFLUOROMETHYL)PHENYL)PROPAN-2-AMINE;4-(Trifluoromethyl)-alpha-methylbenzeneethanamine;alpha-Methyl-p-trifluoromethylphenethylamine;Phenethylamine, alpha-methyl-p-trifluoromethyl-;MFCD01708017;SCHEMBL265675;CHEMBL3247894;DTXSID00936719;BBL101644;STL555440;AKOS000154802;AKOS017343122;MB02012;MS-20243;1-(4-trifluoromethylphenyl)-2-aminopropane;LS-103692;2-Amino-1-[(4-trifluoromethyl)phenyl]propane;EN300-57912;N10877;P-1726;1-Methyl-2-(4-trifluoromethyl-phenyl)-ethylamine;2-AMINO-1-[(4-TRIFLUOROMETHYL)PHENYL] PROPANE;Benzeneethanamine, .alpha.-methyl-4-(trifluoromethyl)-

Suppliers and Price of 1-[4-(Trifluoromethyl)phenyl]propan-2-amine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

TRC
2-Amino-1-[4-(trifluoromethyl)phenyl]propane
100mg
$ 60.00

American Custom Chemicals Corporation
1-(4-(TRIFLUOROMETHYL)PHENYL)PROPAN-2-AMINE 95.00%
5MG
$ 496.52

Total 11 raw suppliers

Chemical Property of 1-[4-(Trifluoromethyl)phenyl]propan-2-amine

Chemical Property:

Vapor Pressure:0.0929mmHg at 25°C
Boiling Point:224.1°C at 760 mmHg
PKA:9.54±0.10(Predicted)
Flash Point:93.6°C
PSA：26.02000
Density:1.152g/cm³
LogP:3.29540
XLogP3:2.6
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:2
Exact Mass:203.09218387
Heavy Atom Count:14
Complexity:171

Purity/Quality:

99%, ^*data from raw suppliers

2-Amino-1-[4-(trifluoromethyl)phenyl]propane ^*data from reagent suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Canonical SMILES:CC(CC1=CC=C(C=C1)C(F)(F)F)N
Uses 2-Amino-1-[4-(trifluoromethyl)phenyl]propane is a monoamine oxidase inhibitor. Amphetamine derivative.

Technology Process of 1-[4-(Trifluoromethyl)phenyl]propan-2-amine

There total 5 articles about 1-[4-(Trifluoromethyl)phenyl]propan-2-amine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 73.0%

: 2341-32-4
1-methyl-1-nitro-2-<4-(trifluoromethyl)phenyl>ethene

: 1626-74-0
1-methyl-2-(4-trifluoromethyl-phenyl)-ethylamine

Guidance literature:: With lithium aluminium tetrahydride; In diethyl ether; for 3h; Inert atmosphere; Reflux;
DOI:10.1039/c1ob06251d

Reference yield:

: 455-19-6
4-Trifluoromethylbenzaldehyde

: 1626-74-0
1-methyl-2-(4-trifluoromethyl-phenyl)-ethylamine

Guidance literature:: Multi-step reaction with 2 steps

1: nBuNH₂

2: LiAlH₄

With lithium aluminium tetrahydride; N-butylamine;
DOI:10.1021/jm00341a011

Reference yield:

: 713-45-1
1-[(4-trifluoromethyl)phenyl]-2-propanone

: 1626-74-0
1-methyl-2-(4-trifluoromethyl-phenyl)-ethylamine

Guidance literature:: With pyridoxal 5'-phosphate; amine transaminase ATA-113; isopropylamine; In aq. phosphate buffer; at 30 ℃; for 24h; pH=7.5; Enzymatic reaction;
DOI:10.1002/adsc.201900179