C₁₅H₁₉IO₅

Base Information

• Chemical Name: C₁₅H₁₉IO₅
• CAS No.: 1384439-29-5
• Molecular Formula: C₁₅H₁₉IO₅
• Molecular Weight: 406.217
• Mol file: 1384439-29-5.mol

Synonyms:C₁₅H₁₉IO₅

Chemical Property of C₁₅H₁₉IO₅

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

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Technology Process of C₁₅H₁₉IO₅

There total 3 articles about C₁₅H₁₉IO₅ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 99.0%

7-(2-iodo-6-methoxyphenoxy)-1,4-dioxaspiro[4.5]decan-8-one (1378372-33-8) → C15H19IO5 (1384439-29-5)

Guidance literature:

With C₅₅H₅₀Cl₂N₂P₂Ru; potassium tert-butylate; hydrogen; In isopropyl alcohol; at 30 ℃; for 3h; under 22801.5 Torr; optical yield given as %ee; enantioselective reaction; Autoclave;

DOI:10.1021/ol300913g

Reference yield:

2-iodo-6-methoxyphenol (111726-46-6) → C15H19IO5 (1384439-29-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 8 h / 80 °C

2: C₅₅H₅₀Cl₂N₂P₂Ru; potassium tert-butylate; hydrogen / isopropyl alcohol / 3 h / 30 °C / 22801.5 Torr / Autoclave

With C₅₅H₅₀Cl₂N₂P₂Ru; potassium tert-butylate; hydrogen; potassium carbonate; In N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1021/ol300913g

Reference yield:

7-bromo-1,4-dioxaspiro[4,5]decan-8-one (943589-83-1) → C15H19IO5 (1384439-29-5)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / N,N-dimethyl-formamide / 8 h / 80 °C

2: C₅₅H₅₀Cl₂N₂P₂Ru; potassium tert-butylate; hydrogen / isopropyl alcohol / 3 h / 30 °C / 22801.5 Torr / Autoclave

With C₅₅H₅₀Cl₂N₂P₂Ru; potassium tert-butylate; hydrogen; potassium carbonate; In N,N-dimethyl-formamide; isopropyl alcohol;

DOI:10.1021/ol300913g

upstream raw materials:

7-bromo-1,4-dioxaspiro[4,5]decan-8-one

7-(2-iodo-6-methoxyphenoxy)-1,4-dioxaspiro[4.5]decan-8-one

2-iodo-6-methoxyphenol

Downstream raw materials:

7-(2-iodo-6-methoxyphenoxy)-1,4-dioxaspiro[4.5]decan-8-one