Methyl 2-(chlorosulfonyl)-6-fluorobenzoate

Base Information

Chemical Name:Methyl 2-(chlorosulfonyl)-6-fluorobenzoate
CAS No.:120257-01-4
Molecular Formula:C₈H₆ClFO₄S
Molecular Weight:252.651
Hs Code.:
European Community (EC) Number:826-892-9

Synonyms:methyl 2-(chlorosulfonyl)-6-fluorobenzoate;120257-01-4;methyl 2-chlorosulfonyl-6-fluorobenzoate;SCHEMBL9620563;CJRQUWXRRINNTQ-UHFFFAOYSA-N;AKOS012606185;methyl2-(chlorosulfonyl)-6-fluorobenzoate;EN300-106176;G58939;METHYL 6-FLUORO-2-CHLOROSULFONYL-BENZOATE

Suppliers and Price of Methyl 2-(chlorosulfonyl)-6-fluorobenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
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price

Total 1 raw suppliers

Chemical Property of Methyl 2-(chlorosulfonyl)-6-fluorobenzoate

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:3
Exact Mass:251.9659357
Heavy Atom Count:15
Complexity:337

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC(=O)C1=C(C=CC=C1S(=O)(=O)Cl)F

Technology Process of Methyl 2-(chlorosulfonyl)-6-fluorobenzoate

There total 5 articles about Methyl 2-(chlorosulfonyl)-6-fluorobenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 86505-94-4
2-amino-6-fluoro-benzoic acid,methyl ester

: 120257-01-4
methyl 2-chlorosulfonyl-6-fluorobenzoate

Guidance literature:: With sulfur dioxide; chlorine; sodium nitrite; hydrogenchloride;
DOI:10.2533/000942904777678226

Reference yield:

: 7447-39-4
copper(II) chloride

: 107-06-2,52399-93-6
1,2-dichloro-ethane

: 86505-94-4
2-amino-6-fluoro-benzoic acid,methyl ester

: 120257-01-4
methyl 2-chlorosulfonyl-6-fluorobenzoate

Guidance literature:: With chlorine; sodium nitrite; In hydrogenchloride; sulfur dioxide; water;

Reference yield:

: 1194-65-6
2,6-dichloro-benzonitrile

: 120257-01-4
methyl 2-chlorosulfonyl-6-fluorobenzoate

Guidance literature:: Multi-step reaction with 4 steps

1: KF; 18-crown-6 / 3 h / 180 °C

2: NH₃ / 10 h / 100 °C

3: 91 percent / HCl

4: 95 percent / NaNO₂; SO₂; Cl₂ / HCl

With hydrogenchloride; potassium fluoride; 18-crown-6 ether; sulfur dioxide; ammonia; chlorine; sodium nitrite; hydrogenchloride; 3: Pinner reaction / 4: Meerwein reaction;
DOI:10.2533/000942904777678226