5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiole-3-thione

Base Information

• Chemical Name: 5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiole-3-thione
• CAS No.: 1023740-28-4
• Molecular Formula: C₁₉H₂₆OS₃
• Molecular Weight: 366.613
• Mol file: 1023740-28-4.mol

Synonyms:5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiole-3-thione

Chemical Property of 5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiole-3-thione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiole-3-thione

There total 5 articles about 5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiole-3-thione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

3-(3,5-di-(tert-butyl)-4-methoxyphenyl)-α-methyl-β-oxo-propanoic acid methyl ester (1023740-44-4) → 5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiole-3-thione (1023740-28-4)

Guidance literature:

With sulfur; tetraphosphorus decasulfide; In 5,5-dimethyl-1,3-cyclohexadiene; for 1.5h; Reflux;

DOI:10.1071/CH09517

Reference yield:

3-(3,5-di-(tert-butyl)-4-methoxyphenyl)-β-oxo-propanoic acid methyl ester (1023740-41-1) → 5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiole-3-thione (1023740-28-4)

Guidance literature:

Multi-step reaction with 2 steps

1: potassium carbonate / methanol / Reflux

2: sulfur; tetraphosphorus decasulfide / 5,5-dimethyl-1,3-cyclohexadiene / 1.5 h / Reflux

With sulfur; tetraphosphorus decasulfide; potassium carbonate; In methanol; 5,5-dimethyl-1,3-cyclohexadiene;

DOI:10.1071/CH09517

Reference yield:

1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethanone (14035-33-7) → 5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiole-3-thione (1023740-28-4)

Guidance literature:

Multi-step reaction with 4 steps

1: potassium carbonate / acetone

2: sodium hydride / tetrahydrofuran; mineral oil / 2 h / Reflux

3: potassium carbonate / methanol / Reflux

4: sulfur; tetraphosphorus decasulfide / 5,5-dimethyl-1,3-cyclohexadiene / 1.5 h / Reflux

With sulfur; tetraphosphorus decasulfide; sodium hydride; potassium carbonate; In tetrahydrofuran; methanol; 5,5-dimethyl-1,3-cyclohexadiene; acetone; mineral oil;

DOI:10.1071/CH09517

upstream raw materials:

3-(3,5-di-(tert-butyl)-4-methoxyphenyl)-α-methyl-β-oxo-propanoic acid methyl ester

3-(3,5-di-(tert-butyl)-4-methoxyphenyl)-β-oxo-propanoic acid methyl ester

1-(3,5-di-(tert-butyl)-4-methoxyphenyl)ethanone

1-(3,5-di-tert-butyl-4-hydroxyphenyl)ethanone

Downstream raw materials:

5-(3,5-di-(tert-butyl)-4-methoxyphenyl)-4-methyl-3H-1,2-dithiol-3-one