2-(Trimethylsilyl)ethyl O-<4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside

Base Information

• Chemical Name: 2-(Trimethylsilyl)ethyl O-<4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside
• CAS No.: 155115-18-7
• Molecular Formula: C₃₂H₄₆O₁₂Si
• Molecular Weight: 650.796
• Mol file: 155115-18-7.mol

Synonyms:2-(Trimethylsilyl)ethyl O-<4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside

Chemical Property of 2-(Trimethylsilyl)ethyl O-<4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(Trimethylsilyl)ethyl O-<4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside

There total 1 articles about 2-(Trimethylsilyl)ethyl O-<4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 72.0%

benzaldehyde dimethyl acetal (1125-88-8) + 2-(trimethylsilyl)ethyl O-<3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside (128716-18-7) → 2-(Trimethylsilyl)ethyl O-<4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside (155115-18-7)

Guidance literature:

With calcium sulfate; toluene-4-sulfonic acid; In N,N-dimethyl-formamide; 1.) r.t., 2 h, 2.) r.t., 16 h;

Reference yield: 88.0%

benzyl bromide (100-39-0) + 2-(Trimethylsilyl)ethyl O-<4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside (155115-18-7) → 2-(Trimethylsilyl)ethyl O-[2-O-benzyl-4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl]-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside (155115-19-8)

Guidance literature:

With sodium hydride; In N,N-dimethyl-formamide; 1.) 0 deg C, 30 min, 2.) r.t., 3 h;

Reference yield:

2-(Trimethylsilyl)ethyl O-<4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside (155115-18-7) → 2-(Trimethylsilyl)ethyl O-(2-O-benzyl-4,6-O-benzylidene-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside (155115-20-1)

Guidance literature:

Multi-step reaction with 2 steps

1: 88 percent / NaH / dimethylformamide / 1.) 0 deg C, 30 min, 2.) r.t., 3 h

2: 82 percent / 2,3-dichloro-5,6-dicyanobenzoquinone / CH₂Cl₂; H₂O / 1 h / Ambient temperature

With sodium hydride; 2,3-dicyano-5,6-dichloro-p-benzoquinone; In dichloromethane; water; N,N-dimethyl-formamide;

upstream raw materials:

benzaldehyde dimethyl acetal

2-(trimethylsilyl)ethyl O-<3-O-(4-methoxybenzyl)-β-D-galactopyranosyl>-(1->4)-β-D-glucopyranoside

Downstream raw materials:

2-(Trimethylsilyl)ethyl O-[2-O-benzyl-4,6-O-benzylidene-3-O-(4-methoxybenzyl)-β-D-galactopyranosyl]-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside

2-(Trimethylsilyl)ethyl O-(2-O-benzyl-4,6-O-benzylidene-β-D-galactopyranosyl)-(1->4)-2,3,6-tri-O-benzyl-β-D-glucopyranoside